Clinical trial · Interventional
Researching Economical Adjuvants to Cancer Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the investigators if combining beta-glucan with single bouts of exercise provides additional benefit. The main questions it aims to answer are: 1. Does beta-glucan change the ability of immune cells to recognize cancer cells? 2. Does exercise change the type of immune cells in the blood? Researchers will compare beta-glucan to a placebo (a look-alike substance with no effect) to see if beta-glucan could improve immune function against cancer. Participants will: 1. Take beta-glucan or a placebo daily for 4 weeks. 2. Visit the laboratory for three exercise tests. 3. Provide blood samples so researchers can study immune system cells.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Healthy Participants | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Beta-glucan | Dietary Supplement | — | UNRESOLVED |
| Placebo | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Beta-glucan
- description
- 375mg of beta-glucan is provided daily for 4 weeks.
- interventionNames
- Dietary Supplement: Beta-glucan
- type
- PLACEBO_COMPARATOR
- label
- Placebo
- description
- 375mg of cellulose daily for 4 weeks.
- interventionNames
- Dietary Supplement: Placebo
Primary outcomes (1)
- measure
- Cellular Cytotoxicity Assessed With Flow Cytometry
- timeFrame
- At baseline, the end of treatment at four weeks, and at eight weeks after a washout phase.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Physically fit enough to engage in maximal exercise. Exclusion Criteria: * BMI \> 40 kg/m2 * Stage 2 hypertension (140/90 mmHg) * Type I or II diabetes * Autoimmune diseases * Overt cardiovascular, respiratory, or neurological disease (e.g., previous heart attack, pacemaker, heart failure, asthma) * Hormone replacement therapy (e.g., androgens, estrogens) * Daily medication usage that may affect immune function (e.g., beta blockers, NSAIDs, corticosteroids, allergy medications) * Current antibiotic use * Heavy alcohol usage (\>2 drinks per day) * Tobacco use within the last 6 months * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Self-reported pregnancy * Prisoners
References
Publications (0)
Data not yet available