Clinical trial · Observational
Impact of Endo-vac Therapy for Esophago-jejunal Anastomotic Leak
Prospective Observational Study on Endo-vac Therapy for Esophago-jejunal Anastomotic Leak
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to assess the impact of endoscopic vacuum therapy in patients who underwent total gastrectomy due to gastric cancer and developed esophago-jejunal anastomotic leakage. The main outcomes to be investigated are the following: Primary endpoint: mortality rate Secondary endpoints: morbidity rate, time from AL diagnosis to discharge, patients satisfactory rate.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagojejunal Anastomotic Leak | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Endo-vac cohort
- description
- Patients who are diagnosed with asophago-jejunal anastomotic leakage will undergo endoscopic vacuum therapy. Local source control may be additionally achieved with para-anastomotic drains.
Primary outcomes (1)
- measure
- Mortality rate
- timeFrame
- 90 days after last endo-vac placement
- description
- Mortality rate associated with endoscopic vacuum therapy
Secondary outcomes (3)
- measure
- Morbidity rate
- timeFrame
- 90 days after last endoscopic vacuum placement
- description
- Rate of complications associated with endoscopic vacuum therapy or ineffective local control
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * patients who developed esophago-jejunal anastomotic leak less than 50% of circumference of anastomosis * patients who developed esophago-jejunal anastomotic leak and remained stable at the moment of diagnosis with no indications for diversion surgery Exclusion Criteria: * unstable patients who developed esophago-jejunal anastomotic leak * patients who developed esophago-jejunal anastomotic leak more than 50% or anastomotic circumference * patients who rejected endoscopic vacuum therapy
References
Publications (0)
Data not yet available