Clinical trial · Observational
Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients
Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients: A Prospective Observational Study of Optic Nerve Sheath Diameter Dynamics
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of surgery for brain tumor removal. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Neoplasm | Brain Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Intracranial Pressure Increase | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ocular Sonography | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- optic nerve sheath diameter dynamics
- timeFrame
- before (in the preoperative holding area) and after the surgery (immediate, 1,2, 4, 6, and 12 hr in ICU).
- description
- the measuremnt of optic nerve sheath diameter and optic nerve sheath diameter to transverse eyeball diamter ratio
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * • Adult patients (\>21 years) undergoing brain tumor resection surgery. * Preoperative imaging-confirmed diagnosis of the tumor. * American Society of Anesthesiologists (ASA) physical status II to IV * Consent to participate in the study. Exclusion Criteria: * • Preexisting ocular conditions affecting the optic nerve or globe integrity, such as glaucoma, thyroid-associated ophthalmopathy, or other optic nerve diseases. * Combined ocular and optic nerve injuries at admission. * History of cranial trauma, prior neurosurgery, or lumbar puncture performed within 2 weeks before the measurement of optic nerve sheath diameter (ONSD). * History of subarachnoid hemorrhage (SAH). * Serious complications that could affect life expectancy, such as hematological disorders or malignancies. * Refusal to participate or withdrawal of consent at any stage.
References
Publications (0)
Data not yet available