Clinical trial · Interventional
Histopathological Findings in En-Bloc vs Conventional Transurethral Resection of Bladder Tumors.
Comparison Between En-Bloc Transurethral Resection Versus Conventional Transurethral Resection of Urinary Bladder Tumors From 2 to 6 cm in Size, Histopathological Findings.
NCT07259798CI-TRIAL-00098759completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to determine whether en-bloc TURBT provides superior histopathological quality and clinical outcomes compared to conventional TURBT in medium-sized bladder tumors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Urinary Bladder Cancer | Malignant Bladder Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bipolar piecemeal TURBT using the same bipolar Karl-Storz resectoscopic platform | Procedure | — | UNRESOLVED |
| En bloc TURBT using a bipolar Karl-Storz resectoscope system fitted with a specialized "flat" resection loop | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group A: Underwent En bloc Bipolar TURBT
- interventionNames
- Procedure: En bloc TURBT using a bipolar Karl-Storz resectoscope system fitted with a specialized "flat" resection loop
- type
- ACTIVE_COMPARATOR
- label
- Group B: Bipolar piecemeal TURBT
- interventionNames
- Procedure: Bipolar piecemeal TURBT using the same bipolar Karl-Storz resectoscopic platform
Primary outcomes (1)
- measure
- the presence of detrusor muscle in histopathologic specimens
- timeFrame
- 10 days post TURBT
- description
- This assessment aims to compare the histopathological outcomes between the tumors obtained from the en bloc bipolar resection versus the conventional method bipolar Trans-Urethral Resection of Bladder Tumor techniques
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Tumor diameter of 2-6 cm * Patients fit for spinal or general anesthesia Exclusion Criteria: * recurrent bladder tumours. * concomitant urothelial cancer of the upper urinary tract * metastatic bladder cancer
References
Publications (2)
- RESULTYang H, Lin J, Gao P, He Z, Kuang X, Li X, Fu H, Du D. Is the En Bloc Transurethral Resection More Effective than Conventional Transurethral Resection for Non-Muscle-Invasive Bladder Cancer? A Systematic Review and Meta-Analysis. Urol Int. 2020;104(5-6):402-409. doi: 10.1159/000503734. Epub 2020 Jan 7. PMID 31910427
- RESULTSun S, Wang H, Zhang X, Chen G. Transurethral Resection of Bladder Tumor: Novel Techniques in a New Era. Bladder (San Franc). 2023 Nov 9;10:e21200009. doi: 10.14440/bladder.2023.865. eCollection 2023. PMID 38022709