Clinical trial · Observational
Tumor-Derived Extracellular Vesicles for Noninvasive Molecular Classification of Kidney Cancer
NCT07243067CI-TRIAL-00104168not yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a correlative (lab-based) study aiming to identify protein markers in urine extracellular vesicles (EVs) that can be used to develop non-invasive molecular tests for patients with renal cell carcinoma (RCC). Aim 1 will use urine collected previously in biorepository. Aim 2 will prospectively collect blood specimens pre and post nephrectomy.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chromophobe Renal Cell Carcinoma | Chromophobe Renal Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Clear-cell Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Kidney Cancer | Malignant Kidney Neoplasm | CURATED_EXACT | 0.92 |
| Papillary Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Renal Cell Carcinoma | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sample collection | Procedure | — | UNRESOLVED |
| Proteomic profiling of urinary EVs | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- Clear-cell RCC
- description
- Participants with clear-cell RCC
- interventionNames
- Other: Proteomic profiling of urinary EVs
- Procedure: Blood sample collection
- label
- Papillary RCC
- description
- Participants with papillary RCC
- interventionNames
- Other: Proteomic profiling of urinary EVs
- Procedure: Blood sample collection
- label
- Chromophobe RCC
- description
- Participants with chromophobe RCC
- interventionNames
- Other: Proteomic profiling of urinary EVs
- Procedure: Blood sample collection
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Urine sample in existing biorepository * High-risk renal cell carcinoma (RCC) per American Urological Association (AUA) guidelines * Scheduled to undergo nephrectomy Exclusion Criteria: * Does not meet inclusion criteria
References
Publications (0)
Data not yet available
No reference posted for this study.