Clinical trial · Interventional
Antrodia Cinnamomea Extract Effects on Lung Cancer Patients' Quality of Life During Chemotherapy
The Effects of Antrodia Cinnamomea Fruiting Body Extract on Quality of Life and Chemotherapy Side Effects in Patients With Lung Cancer Undergoing Platinum-Based Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized trial will test whether Antrodia cinnamomea supplement improves quality of life in lung cancer patients receiving platinum-based chemotherapy. Participants at Tri-Service General Hospital will be randomized to receive either Antrodia cinnamomea capsules or placebo for 3 months, with follow-up to 6 months (24 weeks). Primary outcomes include nausea/vomiting scores, sleep quality, quality of life, and cancer symptoms.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer (Diagnosis) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Antrodia cinnamomea supplement | Dietary Supplement | — | UNRESOLVED |
| Turmeric-Probiotic Group | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Antrodia cinnamomea plus turmeric and probiotics
- description
- Participants will receive capsules containing Antrodia cinnamomea extract, turmeric, and probiotics taken orally once daily for 3 months during platinum-based chemotherapy treatment.
- interventionNames
- Dietary Supplement: Antrodia cinnamomea supplement
- type
- ACTIVE_COMPARATOR
- label
- Turmeric and probiotics only
- description
- Participants will receive capsules containing turmeric and probiotics (without Antrodia cinnamomea) taken orally once daily for 3 months during platinum-based chemotherapy treatment.
- interventionNames
- Dietary Supplement: Turmeric-Probiotic Group
Primary outcomes (4)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Pathologically and radio-graphically diagnosed lung cancer * Age greater than 18 years * Received platinum-based chemotherapy * Life expectancy of six months or longer Exclusion Criteria: * Inability to comply with timely supplementation administration. * Within 14 days prior to trial entry, laboratory data showing abnormal liver function, abnormal kidney function * Within 30 days prior to trial entry, unexplained fever ≥38.5°C for 7 consecutive days or chronic diarrhea for 15 consecutive days. * Currently receiving hormone therapy. * Major cardiac disease or arrhythmia severe enough that the attending physician considers the patient unsuitable for trial participation. * Major neuropathy. * Patients with currently active acute infections. * Patients with known allergies/allergic reactions to the investigational product or any components in their formulations. * Patients currently taking supplements containing Antrodia camphorata extract.
References
Publications (0)
Data not yet available