Clinical trial · Interventional
Exercise Prehabilitation of Breast Cancer
The Impact of Exercise Prehabilitation on Upper Extremity Range of Motions, Functionality and Quality of Life in Breast Cancer Survivors: A Prospective Clinical Trial
NCT07240584CI-TRIAL-00097748Prehab of BCcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective prehabilitation trial evaluated the effectiveness of an individualized exercise program initiated before breast cancer surgery and maintained for 12 months. The intervention aimed to promote functional recovery and improve patient-reported outcomes.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Fatigue | — | UNRESOLVED | — |
| Lymphedema | — | UNRESOLVED | — |
| Postoperative Recovery | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
| Shoulder Dysfunction | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise-Based Prehabilitation Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Single Group Assignment
- interventionNames
- Behavioral: Exercise-Based Prehabilitation Program
Primary outcomes (3)
- measure
- Shoulder Range of Motion
- timeFrame
- baseline, 1st-3rd-6th-12th month
- description
- Measurement of Flexion, Abduction, Internal and External Rotation of Shoulder with goniometer
- measure
- Pain Intensity
- timeFrame
- baseline, 1st-3rd-6th-12th month
- description
- measure of pain with VAS (Visual analog scale)
- measure
- Functional Outcomes
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients diagnosed with breast cancer scheduled for surgical treatment * Age ≥ 18 years * Able to perform exercise * Provided informed consent Exclusion Criteria: * Metastatic disease * Prior upper limb injury or neurologic impairment * Inability to comply with exercise program * Postoperative chemotherapy before the 3rd month
References
Publications (4)
- RESULTBrahmbhatt P, Sabiston CM, Lopez C, Chang E, Goodman J, Jones J, McCready D, Randall I, Rotstein S, Santa Mina D. Feasibility of Prehabilitation Prior to Breast Cancer Surgery: A Mixed-Methods Study. Front Oncol. 2020 Sep 25;10:571091. doi: 10.3389/fonc.2020.571091. eCollection 2020. PMID 33072603
- RESULTMichael CM, Lehrer EJ, Schmitz KH, Zaorsky NG. Prehabilitation exercise therapy for cancer: A systematic review and meta-analysis. Cancer Med. 2021 Jul;10(13):4195-4205. doi: 10.1002/cam4.4021. Epub 2021 Jun 10. PMID 34110101
- RESULTAlicia DRJ, Manuel GS, Ignacio CVA. Physical prehabilitation in patients with breast cancer: a systematic review. Support Care Cancer. 2025 Jan 6;33(1):71. doi: 10.1007/s00520-024-09122-w. PMID 39757306
- DERIVEDAkin T, Akin M, Kucuk AI, Iriagac Y. The impact of exercise prehabilitation on upper extremity range of motions, functionality and quality of life in breast cancer survivors: a prospective clinical trial. BMC Sports Sci Med Rehabil. 2026 Jan 29;18(1):122. doi: 10.1186/s13102-026-01534-x. PMID 41612417