Clinical trial · Observational
AST/ALT & MPV/Platelets Ratios in Breast Cancer
Role of AST/ALT Ratio & MPV/Platelets Count Ratio in Breast Cancer
NCT07238127CI-TRIAL-00099345not yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This retrospective study aims to evaluate the association between AST/ALT ratio and MPV/platelets count ratio with breast cancer in a case-control study.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| AST/ALT Ratio | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| MPV/Platelets Ratio | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- 1. Difference in AST/ALT ratio between breast cancer patients and controls 2. Difference in MPV/Platelet count ratio between breast cancer patients and controls
- timeFrame
- Baseline
- description
- Comparison of mean AST/ALT ratio and MPV/platelets count ratio between the two groups
Secondary outcomes (1)
- measure
- 1. Diagnostic performance of AST/ALT ratio for distinguishing breast cancer patients from controls 2. Diagnostic performance of MPV/Platelet count ratio for distinguishing breast cancer patients from controls
- timeFrame
- baseline
- description
- Sensitivity, specificity and AUC calculated from AST/ALT ratio and MPV/platelets count ratio values
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed patients of breast cancer admitted to South Egypt Cancer Institute at different stage of the disease Exclusion Criteria: 1. other malignant diseases 2. male breast cancer
References
Publications (1)
- BACKGROUNDDivsalar B, Heydari P, Habibollah G, Tamaddon G. Hematological Parameters Changes in Patients with Breast Cancer. Clin Lab. 2021 Aug 1;67(8). doi: 10.7754/Clin.Lab.2020.201103. PMID 34383417