Clinical trial · Interventional
Effectiveness of a Guided Self-Help CBT Manual 'KOK' in Cancer Patients
Effectiveness of the Guided Self-Help CBT Manual 'Khushi or Khatoon (KoK)' in Cancer Patients: A Randomised Controlled Trial
NCT07236164CI-TRIAL-00098133not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aimed to assess the feasibility, acceptability, and preliminary efficacy of the Guided self-help CBT intervention 'Khushi or Khatoon' to treat anxiety and depression, and enhance quality of life and satisfaction with treatment in cancer patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Depression | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Culturally adapted guided self-help CBT manual 'Khushi or Khatoon (KoK)' | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Culturally adapted guided self-help CBT manual 'Khushi or Khatoon (KoK)'
- description
- Participants will receive the culturally adapted Guided self-help CBT manual 'Khushi or Khatoon (KoK)'. The manual includes eight modules on managing anxiety and depression. The modules focus on cognitive restructuring, problem solving, behavioural activation, conflict management, interpersonal relationships, mental health and well-being, and self-care. Each module is delivered over one week. The intervention uses culturally appropriate stories, drawings, and examples from local folklore and religious contexts to describe the concepts of CBT.
- interventionNames
- Behavioral: Culturally adapted guided self-help CBT manual 'Khushi or Khatoon (KoK)'
- type
- NO_INTERVENTION
- label
- Treatment as Usual
- description
- Receive usual care, which may include standard support provided by the oncology team.
Primary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Adults (≥ 18 years) * Clinical diagnosis of cancer * Experiencing moderate to severe psychological distress (HADS score ≥ 8) * Able to read and write the Urdu language * Willing to participate and provide informed consent Exclusion Criteria: * Severe psychiatric conditions requiring immediate intervention/hospitalisation * Cognitive impairments preventing understanding of the manual/therapy * Visual impairments that may prevent the reading of the manual * Already been receiving any psychological therapy
References
Publications (0)
Data not yet available
No reference posted for this study.