Clinical trial · Observational
Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System
NCT07219134CI-TRIAL-00108619completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is being done to see if researchers can find a better way to image a patient's tumor during radiation treatment.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Genitourinary System Carcinoma | Genitourinary System Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Malignant Pelvic Neoplasm | Malignant Pelvic Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Non-Interventional Study | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational
- description
- Patients undergo lower beam energy CBCT scan once during standard of care radiation therapy on study.
- interventionNames
- Other: Non-Interventional Study
Primary outcomes (2)
- measure
- Image quality- Mean
- timeFrame
- Up to 2 years
- description
- The primary analysis will compare imaging quality endpoints processed by DE-CBCT and the standard of care SE-CBCT, with the latter representing the standard clinical acquisition. Descriptive statistics will be computed for the image quality metrics from each imaging modality and for the difference in metrics between the modalities. A paired t-test or Wilcoxon signed-rank test will compare the distribution of the image quality metrics between DE-CBCT and standard of care SE-CBCT. Secondary analysis will compare image quality endpoints between DE-CBCT and standard of care conventional planning CT.
- measure
- Image quality- median
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * \* Patients with pelvis or genitourinary (GU) cancer requiring standard of care radiotherapy treatment * All adults, defined as individuals of 18 years of age or greater * Radiotherapy treatment will be performed on the Varian Ethos radiotherapy system * Ability to understand and the willingness to sign a written informed consent Exclusion Criteria: * \* Minors, defined as individuals less than 18 years of age * Pregnant or nursing female
References
Publications (0)
Data not yet available
No reference posted for this study.