Clinical trial · Interventional
Manual Lymph Drainage for External Lymphedema
The Effect of Manual Lymph Drainage for Cancer Treatment-related External Lymphedema in the Head and Neck - a Pilot and Feasibility Study of a Randomized Controlled Trial
NCT07215169CI-TRIAL-00096467MLD-HNrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will evaluate the feasibility of a randomized controlled trial. The future randomized controlled trial will compare two groups following different intensities of manual lymphatic drainage for external head- and neck lymphedema among persons treated with radiotherapy for head- and neck cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphedema Due to Radiation | — | UNRESOLVED | — |
| Lymphedema of Face | — | UNRESOLVED | — |
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Radiotherapy Side Effect | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| HIT | Other | — | UNRESOLVED |
| LIT | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- HIT
- description
- High-intensity treatment with manual lymphedema drainage.
- interventionNames
- Other: HIT
- type
- OTHER
- label
- LIT
- description
- Low-intensity treatment with manual lymphedema drainage, which is the standard treatment.
- interventionNames
- Other: LIT
Primary outcomes (1)
- measure
- Recruitment rate, retention rate, adverse events, and ability to collect outcomes
- timeFrame
- Two and twelve weeks after inclusion
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * • a previous diagnosis of oropharyngeal cancer (all histological types are accepted) * curative treatment with (chemo)radiotherapy to at least 68Gy at the primary site completed no more than 1 year before the study inclusion * age \>18 years * ability to give written and informed consent. Exclusion Criteria: * • pregnancy * surgery or Botox injections in the tissue of the head and neck area * Locoregional deep infection i.e., suspected abscess at the scheduled time points for measurements. * prior daily treatment with Self MLD * other treatment of head and neck lymphedema, for example compression * psychiatric disorders * substance abuse problems
References
Publications (0)
Data not yet available
No reference posted for this study.