Clinical trial · Interventional
Evaluating the Feasibility and Preliminary Effects of BE+
Evaluating the Feasibility and Preliminary Effects of a Remotely Delivered Dyad-Based Intervention Incorporating Resistance Training to Improve Fitness in Individuals With Non-Small-Cell Lung Cancer and in Their Partners
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This non-randomized, single group study will test a 12-week, behavioral intervention for physical activity and stress management for survivors of non-small cell lung cancer (NSCLC) and a partner (family member or friend). The goals of this intervention, Breathe Easier+ (BE+), are to increase overall physical activity and overall fitness and to reduce symptoms (fatigue, breathlessness, sleep, and stress). The aim of this study is to evaluate the enrollment, retention, adherence, participation, and acceptability of the 12-week BE+ among NSCLC survivors and their partners. The study also aims to: 1. Explore preliminary intervention effects of BE+ on increasing physical activity and overall fitness (measured by 7-day Fitbit wear, step-in-place test, chair sit-and-stand, arm curl test, and balance test) from baseline to post-intervention among NSCLC survivors and their partners. 2. Explore preliminary effects of BE+ for improvement in stress response, symptom burden (fatigue, dyspnea), sleep, and HRQL from baseline to post-intervention among NSCLC survivors and their partners. Participants will receive education, social support, coaching, a guided walking program, supervised resistance training (RT), and meditations delivered via digital technology (tablet, smartphone, and Fitbit).
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer (Non-Small Cell) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
| Physical Activity | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
| Resistance Training | — | UNRESOLVED | — |
| Self-management Behavior | — | UNRESOLVED | — |
| Stress | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Breathe Easier+ | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Breathe Easier+
- description
- Breathe Easier+ includes guided instruction using a digital manual, a walking program, RT training sessions, a weekly telephone coaching call, daily text messages, and assessments at three time points.
- interventionNames
- Behavioral: Breathe Easier+
Primary outcomes (1)
- measure
- Evaluate the feasibility of the 12-week BE+ (BE with RT) among NSCLC survivors and their partners (dyads).
- timeFrame
- 12 weeks
- description
- Feasibility will be evaluated on: 1. Enrollment (25% of eligible participants), 2. Retention (80% of participants at study completion), 3. Adherence (80% to complete instruments at time points 1-3; Fitbit wear \>5 days each week for 12 weeks), 4. Participation (80% to log physical activity weekly, log breathing exercises weekly, set goals weekly, attend 2 resistance training sessions weekly, participate in weekly phone call, and read daily text messages),
Secondary outcomes (6)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Survivors of NSCLC who have completed definitive treatment within the last 2 years. * All participants must have a health clearance for physical activity signed by a healthcare provider; have Wi-Fi access; be able to provide informed consent; and be able to speak and read English. Exclusion Criteria: * Survivors on current definitive treatment. * All participants with a history of recurrent falls; a substantial mobility impairment related to chronic disease or injury; and lack of physical activity readiness as determined by a healthcare provider.
References
Publications (27)
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