Clinical trial · Interventional
Intraoperative Paravertebral Block and Postoperative Complications
Perioperative Paravertebral Block Reduces Postoperative Complications in Thoracic Surgery: An Observational Study
NCT07211529CI-TRIAL-00096416IPVB and POCsrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
Conditions
Conditions (11)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Respiratory Distress Syndrome (ARDS) | — | UNRESOLVED | — |
| Atelectasis | — | UNRESOLVED | — |
| Bronchopleural Fistula | — | UNRESOLVED | — |
| Bronchospasm | — | UNRESOLVED | — |
| Lung Cancer (Diagnosis) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
| Pleural Effusion Due to Another Disorder (Disorder) | — | UNRESOLVED | — |
| Pneumothorax | — | UNRESOLVED | — |
| Pulmonary Embolism (Diagnosis) | — | UNRESOLVED | — |
| Pulmonary Infections | — | UNRESOLVED | — |
| Respiratory Failure Without Hypercapnia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Paravertebral Block (PVB) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Paravertebral Block (PVB)Group
- description
- Participants in this arm will receive a paravertebral nerve block (PVB) performed intraoperatively under ultrasound guidance prior to the thoracic surgical procedure. The block will target the relevant thoracic vertebral levels corresponding to the surgical site. Standard local anesthetic agents will be administered according to institutional protocols. This intervention aims to provide perioperative analgesia, reduce postoperative pain, and potentially decrease the incidence of postoperative complications. All participants will also receive standard intraoperative monitoring and anesthesia management as per routine clinical practice.
- interventionNames
- Procedure: Paravertebral Block (PVB)
- type
- NO_INTERVENTION
- label
- Control Group
- description
- Participants in this arm will receive standard perioperative analgesia without the administration of a paravertebral block. Pain management will follow institutional protocols, which may include systemic opioids, non-steroidal anti-inflammatory drugs (NSAIDs), or other conventional analgesic methods. All participants will undergo the thoracic surgical procedure under standard intraoperative monitoring and anesthesia management as per routine clinical practice. This arm serves as the control group for evaluating the clinical effects of intraoperative paravertebral block on postoperative pain and complication rates.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Male or female participants aged 18 years or older. 2. Scheduled to undergo thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS) or Robotic-Assisted Thoracoscopic Surgery (RATS), including wedge resection, segmentectomy, lobectomy, or mediastinal surgery. 3. Signed informed consent obtained prior to study participation. - Exclusion Criteria: 1. Patients who refuse to provide informed consent. 2. Anesthesiologists who have not received training in ultrasound-guided paravertebral block (PVB-US). 3. History of ipsilateral thoracic surgery. 4. Conversion to open thoracotomy during the procedure. 5. Patients who did not complete the scheduled surgery due to disease progression or medical reasons. 6. Patients who are lost to follow-up or refuse postoperative follow-up. -
References
Publications (0)
Data not yet available
No reference posted for this study.