Clinical trial · Observational
Advanced Ultrasound Signal Processing of Suspicious Breast Images
Advanced Ultrasound Beamforming Methods for Breast Imaging
NCT07206888CI-TRIAL-00096521AUSPICIOUSenrolling by invitationClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to investigate recent developments in ultrasound signal processing to determine if these new techniques can enhance the visibility of important features of interest in breast ultrasound images. Ultrasound signals obtained from both standard ultrasound imaging and ultrasound imaging combined with light (also known as photoacoustic imaging) will be investigated.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Breast Cyst | — | UNRESOLVED | — |
| Microcalcification | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Imaging | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (6)
- measure
- Image quality
- timeFrame
- baseline
- description
- compare advanced beamforming and benchmark against a conventional beamforming technique by measuring and comparing standard image quality metrics
- measure
- Number of microcalcifications
- timeFrame
- baseline
- measure
- Binary visibility of microcalcifications
- timeFrame
- baseline
- description
- Clinicians (members of study team) will be shown images and record 'yes' if microcalcifications are present and 'no' if not.
- measure
- Subjective ratings
- timeFrame
- baseline
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female adults (age \>18 years) with at least one of the following: * Macrocalcification(s) detected in x-ray 2D or 3D mammography images * Macrocalcification(s) located next to cyst (or other identifiable landmark on an ultrasound image) * A cyst, mass, or finding detected in diagnostic/screening ultrasound or mammography Exclusion Criteria: (when performing ultrasound imaging only) * Children (age \< 18 years) are excluded (when performing ultrasound imaging with light, i.e., optoacoustic imaging) * Children (age \< 18 years) are excluded * Is pregnant * Has open sores including insect bites, rash, poison ivy, and chafing on the skin of the ipsilateral breast * Is experiencing phototoxicity associated with currently taking, or having taken, photosensitizing agents within the previous 72 hours such as sulfonamides, ampicillin, tetracycline * Is currently undergoing phototherapy * Has a history of any photosensitive disease (e.g., porphyria, lupus erythematosus) or is undergoing treatment for a photosensitive disease and is experiencing photosensitivity
References
Publications (0)
Data not yet available
No reference posted for this study.