Clinical trial · Observational
Global Research on Appearance in Cancer (GRACE)
The GRACE Study - Global Research on Appearance in Cancer
NCT07195448CI-TRIAL-00096055GRACErecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gaining insight into how weight loss is perceived by persons with advanced cancer, and identifying potential differences related to gender and country of residence, is essential for developing comprehensive, equitable, gender-sensitive recommendations for medical nutrition therapy, with the aim of improving disease outcome.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Body image
- timeFrame
- 2025-2027
- description
- The primary outcome measure of the GRACE study is to measure body image, by using Body Image Scale (BIS). The scoring model contains of four possible responses computing a maximum summary score of 21. The possible responses range from "not at all" (0 points) to "very much" (3 points). A higher score indicate a more distressed body image.
Secondary outcomes (1)
- measure
- Body Image, weight loss, percent weight loss and appetite
- timeFrame
- 2025-2027
- description
- Weight loss measured in kilograms and percent lost compared to weight prior to cancer diagnosis. Appetite measured by using Edmonton Symptom Assessment Scale (ESAS). Appetite is rated between 0 (best possible appetite) to 10 (no appetite).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of cancer * Must be able to understand the consent form Exclusion Criteria: \- Expected survival time \< 3 months
References
Publications (1)
- DERIVEDGoodrose-Flores C, Bonn S, Trolle Lagerros Y, Arends J, Blum D, Figueroa Donoso C, Frazier H, Lin SA, Romboli E, Hoang Van M, Nguyen NB, Nguyen V, Perez-Cruz PE, Bjorkhem-Bergman L. Cross-sectional study of gender differences in the perception of body image during cancer-induced weight loss: study protocol for the GRACE study (Global Research on Appearance in Cancer). BMJ Open. 2026 Jul 15;16(7):e116342. doi: 10.1136/bmjopen-2026-116342. PMID 42457417