Clinical trial · Interventional
Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hereditary Cancer Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Natera empower comprehensive hereditary cancer panel | Device | — | UNRESOLVED |
| Obstetrical carrier screening | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm A: Hereditary cancer testing
- description
- Hereditary Cancer screenings testing and Obstetric Cancer Screening
- interventionNames
- Device: Natera empower comprehensive hereditary cancer panel
- Device: Obstetrical carrier screening
- type
- ACTIVE_COMPARATOR
- label
- Arm B: No hereditary caner testing
- description
- Obstetric Cancer screening test only
- interventionNames
- Device: Obstetrical carrier screening
Primary outcomes (1)
- measure
- Percentage of Participants Who Complete Both HCS and OCS
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion criteria: * Age: 18 years - 55 years * Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site * Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider * Patients with prior OCS but planned to repeat OCS are eligible * Patients can speak and read in English or Spanish Exclusion criteria: * Patients who have previously completed a multigene hereditary cancer syndrome panel * Patients that have a hematologic cancer or hematologic pre-cancer * Patients who have a history of an autologous bone marrow transplant
References
Publications (0)
Data not yet available