Clinical trial · Interventional
Plant-Based Nutrition for Breast or Endometrial Cancer
A Randomized Controlled Trial of Behavioral Education and Nutrition Delivery in Women With Metastatic Breast and Endometrial Cancer. (The BEND-MBEC Study)
NCT07189702CI-TRIAL-00107569BEND-MBECnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a randomized controlled trial of a whole food, plant-based (WFPB) dietary intervention among women with metastatic breast or endometrial cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Metastatic | Endometrial Neoplasm | PROBABILISTIC | 0.70 |
| Endometrial Cancer Stage IV | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control | Other | — | UNRESOLVED |
| Whole Food, Plant-Based Diet with Behavioral Education and Support | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Control
- description
- Regular Diet with Cancer-Related Wellness Education and Support
- interventionNames
- Other: Control
- type
- EXPERIMENTAL
- label
- Whole Food, Plant-Based Diet with Behavioral Education and Support
- description
- Whole Food, Plant-Based Diet with Behavioral Education and Support
- interventionNames
- Other: Whole Food, Plant-Based Diet with Behavioral Education and Support
Primary outcomes (2)
- measure
- Mean Change in Dietary Adherence at 13 and 26 Weeks
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: • Female sex (as assigned at birth), aged 18 years or older * A confirmed diagnosis of endometrial or metastatic breast cancer. All subtypes are eligible * Treating oncologist approval and expected survival of at least six months * Undergoing any systemic treatment including hormonal, cytotoxic, targeted monoclonal antibody or small molecule kinase inhibitors or any combination of the above. Women who have active cancer and have been recommended but declined systemic treatment are also eligible. * Willing to adopt a strict, whole-foods, plant-based diet * Willing and able to comply with the WFPB protocol for the duration of the study including scheduled testing, Zoom meetings, and office visits * Able to speak and read English fluently. * Women with plans for radiation therapy or surgery are also eligible provided that they meet all other eligibility criteria. Exclusion Criteria: • BMI ≤ 20.0 kg/m2 * Inability to tolerate a normal diet * Active malabsorption syndrome at time of consent, as determined by study physicians (i.e. Crohn's disease, bowel surgery) * Any food allergies or intolerances that would interfere with study compliance * Recent consumption (in the past six months) of a vegan diet * eGFR \< 30 on ≥ two lab tests in the past six months * Serum potassium \> 5.4 in the past six months * Current insulin or sulfonylurea use * Current warfarin use (non-vitamin K antagonist allowed) * High-risk alcohol use (\>7 drinks/wk) * Illicit substance use (not including marijuana) * Cognitive impairment or psychiatric disorder impairing ability to give consent.
References
Publications (0)
Data not yet available
No reference posted for this study.