Clinical trial · Observational
Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
Dynamic Monitoring and Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main goal of this study is to follow patients with functional adrenal tumors during the time before and after their surgery. The main questions it aims to answer are: * What heart and blood pressure changes do patients with different types of adrenal tumors have before surgery? * What factors affect how the heart and blood pressure recover after surgery? * Do the heart and blood pressure conditions before surgery influence recovery and the risk of heart or brain problems after surgery? Patients will have heart ultrasound checks and health monitoring before and after surgery. The results will help doctors choose the right medicines before surgery, better understand possible risks during the operation, and make safer treatment plans for patients with functional adrenal tumors.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adrenal Tumor | Adrenal Gland Neoplasm | ALIAS | 0.90 |
| Cushing s Syndrome | — | UNRESOLVED | — |
| Pheochromocytoma/Paraganglioma (PPGL) | — | UNRESOLVED | — |
| Primary Aldosteronism | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (3)
- label
- primary aldosteronism
- label
- Cushing s Syndrome
- label
- Pheochromocytoma/Paraganglioma (PPGL)
Primary outcomes (1)
- measure
- Recovery of cardiac function after adrenal surgery
- timeFrame
- from enrollment to 4,24,48 weeks after surgery
- description
- global longitudinal stress
Secondary outcomes (1)
- measure
- Recovery of blood pressure after adrenal surgery
- timeFrame
- from enrollment to 4,24,48 weeks after surgery
- description
- Decrease in 24h average blood pressure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed in the Department of Urology, Peking University First Hospital with pheochromocytoma and paraganglioma (PPGL), primary aldosteronism (PA), or Cushing syndrome (CS); * Written informed consent obtained. Exclusion Criteria: * Patients with PPGL, PA, or CS who receive medication or conservative treatment and are not eligible for surgical resection; * Patients with communication disorders or severe physical impairments such as aphasia, or visual/hearing disabilities; * Patients with severe mental illness who cannot cooperate with the study; * Pregnant women or patients otherwise deemed unsuitable for participation by the investigators.
References
Publications (0)
Data not yet available