Clinical trial · Observational
Detection of Disease Marker Factors in Cyst Fluid
Measurement of MMP-8, MMP-9, RANKL, MIP-1alpha in Biopsy Samples From Odontogenic Cyst Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this observational study is to examine the cyst fluid obtained after a puncture procedure performed for cyst diagnosis in participants with cystic lesions on clinical and radiological examination.The main question it aims to answer is: \- What is the exact mechanism of formation of odontogenic cysts? Biomarkers in the cyst fluid obtained after a puncture procedure performed as part of the diagnosis and treatment process of odontogenic cysts will be examined. The aim of this study is to gain insight into cyst pathology by examining the levels of biomarkers in odontogenic cyst fluid.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biomarkers | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cyst fluid examination | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- individuals with odontogenic cysts
- description
- The cyst fluid obtained during the puncture will be collected in a tube and centrifuged. The clear liquid remaining on top will be transferred to an Eppendorf tube and stored at -80 degrees. After all samples are collected, they will be analyzed using the ELISA method.
- interventionNames
- Other: cyst fluid examination
Primary outcomes (4)
- measure
- MMP-8 concentration level in cyst fluid
- timeFrame
- through study completion, an average of 6 months
- description
- Cyst fluids aspirated during the puncture will be centrifuged using a centrifuge and stored at -80 degrees Celsius in Eppendorf tubes until examined. After all samples are collected, the MMP-8 concentration level will be measured.
- measure
- MMP-9 concentration level in cyst fluid
- timeFrame
- through study completion, an average of 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Individuals diagnosed with cysts 2. Individuals who are not pregnant or breastfeeding 3. Individuals who agree to sign the informed consent form Exclusion Criteria: 1. Systemically ill individuals who are contraindicated for surgery. 2. Individuals who do not wish to sign the informed consent form. 3. Individuals who are pregnant, breastfeeding, or using oral contraceptives will be excluded.
References
Publications (0)
Data not yet available