Clinical trial · Interventional
Brain Areas of Cognitive Functions: a Study in Awake Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research project focuses on low-level cognitive functions such as perception (auditory, visual, etc.) and high-level cognitive functions (memory, language, temporal estimation, etc.). It aims to better understand the brain bases of these functions as well as their overlap (i.e., brain bases considered to be involved in different functions). To this end, various cognitive tasks will be performed before and during awake brain surgery, allowing us to determine the involvement of different areas in the task being performed. Comparing performance between the pre-test and the intraoperative test will help determine the potential involvement of the tested area.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cerebral Tumor | Cerebral Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Short version of cognitive testing during surgery | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Pré-End
- description
- The day before surgery, brain tumor patients will be offered long-form cognitive tests. If the results of the cognitive tests are not consistent with the literature, this suggests that the tumor is affecting pre-contact time perception. These patients will not be tested during surgery.
- type
- EXPERIMENTAL
- label
- Pré-Per
- description
- The day before surgery, brain tumor patients will be offered long-form cognitive tests. If the results of the cognitive tests are consistent with the literature, the short-form cognitive tests will be offered during awake surgery.
- interventionNames
- Behavioral: Short version of cognitive testing during surgery
Primary outcomes (1)
- measure
- development of an atlas mapping the brain regions involved in each major cognitive function
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with a brain tumor * Aged 18 to 75 years * Signed informed consent * Vision that is corrected or adequate for the purposes of an experiment with visual stimuli * Hearing that is corrected or adequate for the purposes of an experiment with auditory stimuli * No known oculomotor disorder * Person affiliated with or benefiting from a social security scheme. * Free, informed, and written consent signed by the participant and the investigator (no later than the day of inclusion and before any examination required by the research) Exclusion Criteria: * Participants under protected status: guardianship, legal safeguard proceedings, or whose consent to participate in the experiment could be due to a severely altered psychological state, as determined by the medical team responsible for the surgery. * History of neurological disease affecting the central nervous system (Parkinson's, Alzheimer's, history of stroke or cerebral infarction) * Pregnant and/or breastfeeding women.
References
Publications (0)
Data not yet available