Clinical trial · Interventional
Ganglion Resection Effectiveness Trial
GangLion Resection Effectiveness Trial (GangLion): a Multicentre, Randomized, Superiority Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn if surgery helps with wrist ganglions in adults. The main question it aims to answer is: * Does surgery result in better patient-reported outcomes and satisfaction over a 6-months follow-up period? Researchers will compare surgery to conservative treatment (self-administered exercises and use of the hand as tolerated) to see if surgery provides superior outcomes. Participants will: * Be randomly assigned to receive either surgery or conservative treatment * Complete questionnaires about wrist pain, function, quality of life, satisfaction, and recovery at 3, 6, and 12 months
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Connective Tissue Disease | — | UNRESOLVED | — |
| Ganglion | — | UNRESOLVED | — |
| Ganglion Cyst | — | UNRESOLVED | — |
| Mucinoses | — | UNRESOLVED | — |
| Wrist Ganglion | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Arthroscopic resection | Procedure | — | UNRESOLVED |
| Conservative treatment | Other | — | UNRESOLVED |
| Open resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Surgery
- interventionNames
- Procedure: Open resection
- Procedure: Arthroscopic resection
- type
- ACTIVE_COMPARATOR
- label
- Conservative treatment
- interventionNames
- Other: Conservative treatment
Primary outcomes (1)
- measure
- Patient-Rated Wrist/Hand Evaluation (PRWHE) pain score
- timeFrame
- 6 months follow-ups
- description
- The PRWHE is a 15-item questionnaire that is designed to measure wrist pain and disability in activities of daily living. Symptoms are described as average over the past week. The PRWHE consists of two subscales: pain and function. The PRWHE pain includes five items with combined score from 0 (no pain) to 50 (worst ever).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * wrist pain located in the ganglion area * diagnosis of ganglion of the wrist, based on clinical examination or imaging findings * age over 18 years * ability to fill out the Finnish or English version of the questionnaires Exclusion Criteria: * pregnant or breast feeding * other known wrist pathology that likely explains the pain * previous surgical treatments of the wrist * wrist ganglion presumed to be related to a work injury
References
Publications (0)
Data not yet available