Clinical trial · Observational
Cognition and Patients With Lung Cancer
Observation of Cognitive Complaints in Patients With Localized, Operable Non-small Cell Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cognitive complaints in patients treated for cancer can impact their quality of life. Studies show that these cognitive complaints may have multifactorial origins and appear at different stages of the care pathway. In a population of patients treated for confirmed localized non-small cell lung cancer (NSCLC), this study aims to detect and monitor the onset of cognitive complaints over time. The timing of the complaints during the treatment, the cognitive functions affected (memory, attention, concentration…), as well as the perceived intensity of the discomfort, will be examined. The study also explores the influence of co-factors such as mood, fatigue, socio-cultural status, and level of social vulnerability on these cognitive complaints.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Localized, Operable Non-small Cell Lung Cancer | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Assessment of the impact of social vulnerability on patient complaints | Other | — | UNRESOLVED |
| Cognitive tests | Other | — | UNRESOLVED |
| Self-questionnaire | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Surgery only
- interventionNames
- Other: Self-questionnaire
- label
- Neoadjuvant treatment (chemotherapy or chemoimmunotherapy) followed by surgery
- interventionNames
- Other: Cognitive tests
- label
- Surgery followed by adjuvant treatment (chemotherapy)
- interventionNames
- Other: Assessment of the impact of social vulnerability on patient complaints
Primary outcomes (1)
- measure
- To examine the onset, intensity and duration of the PCI (Perceived Cognitive Impairment) score
- timeFrame
- 12 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 74 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patient aged 18 to 74 years * Suspected or confirmed localized and operable non-small cell lung cancer (NSCLC) * Surgical treatment with or without perioperative systemic medical therapy * Ability to independently complete self-questionnaires via the Cleanweb platform * Patients with access to a phone, tablet, or computer at home to complete the electronic self-questionnaires. Exclusion Criteria: * Known pre-existing cognitive disorders * Presence on the day of inclusion of one or more factors causing mental confusion: electrolyte imbalances, renal failure, hepatic failure, infections, bladder distension, fecal impaction * Known psychiatric or neurological diseases (e.g., multiple sclerosis, Parkinson's disease, dementia, stroke, traumatic brain injury with loss of consciousness) * Current use of neuroleptic treatments * History of cancer treatment within the past 10 years * Fibromyalgia * Individuals who cannot read French or are not French-speaking * Patients who have never attended school
References
Publications (0)
Data not yet available