Clinical trial · Interventional
Supporting Treatment Resilience With Optimized Nutrition and Guided Exercise in Head and Neck Cancer Patients Undergoing Chemoradiation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study to find out whether a structured lifestyle intervention-combining nutrition counseling, guided exercise, and wellness education-can help reduce treatment-related side effects and improve physical function, resilience, and quality of life in patients with head and neck cancer undergoing chemoradiation therapy (chemoRT). Benefits of research cannot be guaranteed but we hope to learn whether this intervention is feasible and acceptable during active cancer treatment, and whether it can help preserve lean body mass, improve strength and endurance, and support emotional well-being. The findings will inform the design of a future larger clinical trial.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 20-Week Lifestyle Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Open Label Arm
- description
- Participate in a 20-week lifestyle program that includes: * Nutrition counseling: Weekly group sessions with an oncology dietitian, including individualized calorie and protein goals. * Exercise: Home-based resistance and mobility exercises twice per week using online videos, and daily walking with self-tracking. * Wellness education: Weekly group sessions focused on stress management, sleep, fatigue, and mindset, facilitated by a health and wellness coach. Five of the 20 sessions will include a Speech, Voice, Swallowing, and Airway Care in Head \& Neck Cancer training series led by a speech pathologist.
- interventionNames
- Behavioral: 20-Week Lifestyle Program
Primary outcomes (9)
- measure
- Feasibility of Program: Recruitment Rate
- timeFrame
- From enrollment to the end of the intervention at 20 weeks
- description
- Percentage of eligible patients who enroll in the study. Unit of Measure: Percentage (%) enrolled compared to not enrolled of eligible participants approached.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adults ≥18 years old with biopsy-confirmed squamous cell carcinoma of the head and neck * Planned for definitive or adjuvant chemoRT * ECOG performance status 0-2 * Ability to participate in light-to-moderate physical activity * Able to provide informed consent Exclusion Criteria: * Severe malnutrition requiring exclusive enteral feeding at baseline * Comorbidities that preclude safe participation in exercise * Cognitive or psychiatric conditions that impair study engagement
References
Publications (0)
Data not yet available