Clinical trial · Interventional
Effects of Aerobic Exercise Training Program in Females With Insulin Resistant Polycystic Ovarian Syndrome
Effects of Supervised Structured Aerobic Exercise Training Program on Serum BDNF, Androgens Level, Menstrual Irregularity and Quality of Life in Females With Insulin Resistant Polycystic Ovarian Syndrome
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Design: RCT Randomized Clinical Trial Non Probability Convenient Sampling Technique Duration of treatment: 25 weeks 2 groups; (group A=30) SSAET +Normal routine medication+ Normal Dietary Plan , Other group (Group B=30) with normal routine medication + Normal Dietary Plan. Patients will be enrolled in experimental group according to speeds test. HYPOTHESIS: Alternate hypothesis: There is difference on the effects of Supervised Structured Aerobic Exercise Training Program on serum BDNF, androgens level, menstrual irregularity and quality of life in females with insulin resistant polycystic ovarian syndrome. Null Hypothesis: There is no difference on the effects of Supervised Structured Aerobic Exercise Training Program on serum BDNF, androgens level, menstrual irregularity and quality of life in females with insulin resistant polycystic ovarian syndrome. OBJECTIVES: To determine the effects of Supervised Structured Aerobic Exercise Training Program on quality of life in women with PCOS. 2\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on BDNF levels in women with PCOS. 3\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on mental health (stress, depression, anxiety) in women with PCOS. 4\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on BMI in women with PCOS. 5\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on menstrual irregularity in women with PCOS. 6\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Aerobic fitness in women with PCOS. 7\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on androgens level in PCOS. 8\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Lipid accumulation product in PCOS. 9\. To determine the effect of Supervised Structured Aerobic Exercise Training Program on Glycemic control in PCOS.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aerobic Exercise | — | UNRESOLVED | — |
| Polycystic Ovarian Syndrome (PCOS) | — | UNRESOLVED | — |
| Walking | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Supervised structured aerobic exercise training | Other | — | UNRESOLVED |
| Walk | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Interventional group- PCOS
- description
- 25 weeks of supervised structured aerobic exercise treatment program will be applied on the females with PCOS in the gym setting.
- interventionNames
- Other: Supervised structured aerobic exercise training
- type
- ACTIVE_COMPARATOR
- label
- Second group- PCOS
- description
- walk will be asked for these patients and their feedback will be taken through cell phone
- interventionNames
- Other: Walk
Primary outcomes (6)
- measure
- Depression Anxiety Stress Scale (DASS)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 35 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 To 35 years Females. * Insulin resistant PCOS type. * Already Diagnosed patients form gynecological department according to the Rotterdam criteria. * Both Married and unmarried females. * Nulliparous females. Exclusion Criteria: * Post pill PCOS, Inflammatory PCOS \& Adrenal PCOS * Any psychological disease or disorder * Any systemic disease other than PCOS (cushing syndrome, thyroid dysfunction, etc) * Orthopedic conditions (including fracture, dislocation, etc) * Any surgery in past 6 months. * Involved in any other exercise regimen at the same time. * Having any specialized diet plan.
References
Publications (1)
- RESULTShakil-Ur-Rehman S, Karimi H, Gillani SA. Effects of supervised structured aerobic exercise training program on fasting blood glucose level, plasma insulin level, glycemic control, and insulin resistance in type 2 diabetes mellitus. Pak J Med Sci. 2017 May-Jun;33(3):576-580. doi: 10.12669/pjms.333.12023. PMID 28811774