Clinical trial · Observational
Construction of A Multimodal Digital Assessment Model for Myasthenia Gravis
NCT07146425CI-TRIAL-00094217recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research is a single-center, exploratory, observational study to be carried out in the outpatient or inpatient ward of the Neurology Department at Huashan Hospital, affiliated to Fudan University. The aim is to develop a digital assessment model for Myasthenia Gravis by gathering multimodal digital phenotypic data from MG patients. This includes physiological signals, facial videos, eye movements, speech, limb movements, various scales, and quality of life metrics.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myasthenia Gravis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Myasthenia gravis patients
- description
- Patients were diagnosed of myasthenia gravis
- label
- Healthy subjects
- description
- Healthy individuals of similar age
Primary outcomes (2)
- measure
- Descriptive Analysis and Comparison of Digital Phenotypic Data across Subgroups
- timeFrame
- At baseline (single study visit)
- description
- Quantitative descriptive analysis of multimodal digital phenotypic data (motor performance, ocular metrics, and speech-derived features) to compare subgroup-specific patterns among patients with myasthenia gravis. Metrics will include summary statistics (mean, standard deviation, distribution profiles) for each modality, with subgroup comparisons performed to assess variability.
- measure
- Correlation Between Digital Evaluation Model and Quantitative Myasthenia Gravis (QMG) Scale
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: For Patients with MG * Patients have a confirmed diagnosis of myasthenia gravis and be over 18 years old. * Patients have the clinical classification of Myasthenia Gravis Foundation of America (MGFA) within I-IV, or be asymptomatic after treatment. * Patients must sign the informed consent form and the privacy confidentiality agreement. For Healthy Participants * Age group matched with MG participants Exclusion Criteria: For Patients with MG * Patients are in the crisis stage of myasthenia gravis (MGFA class V) and unable to cooperate with scoring. * Patients are with severe cardiopulmonary diseases and unable to cooperate with the scoring. * Patients with any psychiatric disorder or cognitive dysfunction that, in the investigator's judgment, may interfere with their participation in the study. * Patients with any other unspecified unstable medical condition.
References
Publications (0)
Data not yet available
No reference posted for this study.