Clinical trial · Observational
Breast Cancer BRAs Study (Breast Cancer Biomechanics of Radiotherapy And Surgery)
Breast Cancer BRAs Study (Breast Cancer Biomechanics of Radiotherapy And Surgery): The Effects of Breast Surgery and Radiotherapy on the Breast Biomechanics and Breast Support Requirements of Women Treated for Breast Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 18, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260918-000001
Summary
Brief summary (as posted)
This study, delivered by Portsmouth Hospitals University NHS Trust in conjunction with the Research Group in Breast Health at the University of Portsmouth \[1\], aims to assess whether it is possible to test breast biomechanics in women who have had surgery with or without radiotherapy for the treatment of breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Patients | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Participants with relevant condition
- label
- Women aged 18 or treated with surgery +/- radiotherapy for breast cancer that affects one of their b
Primary outcomes (1)
- measure
- To determine the feasibility of recruitment to a breast biomechanics study in women treated for early breast cancer with surgery +/- adjuvant radiotherapy.
- timeFrame
- From enrollment to the end of study [through study completion, an average of 1 year]
- description
- To identify: Number of patients eligible. Number of patients approached. Number of patients who give informed consent. Number of patients who withdraw after consent before participation. Number of patients who withdraw during follow-up. Number of patients lost to follow-up. Completeness of data per participant. Barriers to participation
Secondary outcomes (1)
- measure
- To determine if it is possible to obtain breast biomechanics data in women treated for early breast cancer with surgery +/- adjuvant radiotherapy.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female * 18 years of age or above * Early or locally advanced breast cancer classified as B5a or B5b (radical treatment intent) * Unilateral breast cancer (contralateral breast used as control) * Receiving or has received breast cancer surgery * +/- Adjuvant radiotherapy * Able to travel to the University of Portsmouth Breast biomechanics laboratory * Participant has capacity to consent. Exclusion Criteria: * Metastatic breast cancer diagnosis * \< 2 weeks post-operative * \< 4 weeks post-radiotherapy * Active post-operative breast infection * Requirement of ongoing breast dressings * Previous breast surgery to contralateral breast * Bilateral breast cancer * Epilepsy (due to strobe on 3D scanner) * Pregnancy or \<6 weeks post-partum * Breastfeeding * Rockwood Frailty score \>5 (or those unable to ambulate un-aided) * Requiring interpreter.
References
Publications (0)
Data not yet available