Clinical trial · Interventional
MRI-guided Dose Intensification Program Locally Advanced Pancreatic Cancer
NCT07132060CI-TRIAL-00094183not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn if the use of dose-escalated MRI-guided irradiation increases the rates of disease control in patients with pancreatic cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MR-guided Irradiation | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Ultrahypofractionation Phase
- description
- MR-Guided Ultrahypofractionation
- interventionNames
- Radiation: MR-guided Irradiation
Primary outcomes (1)
- measure
- Overall Survival
- timeFrame
- 2-years
- description
- A. To achieve a 1-year survival of 85%.
Secondary outcomes (1)
- measure
- Adverse Events
- timeFrame
- 2-years
- description
- To decrease grade 4-5 gastrointestinal events to less than 5%.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Selection criteria includes patients with unresectable and borderline resectable and medically inoperable pancreatic cancer that will receive neoadjuvant chemotherapy followed by chemoirradiation. * No prior radiation therapy to the target areas; * Karnofsky performance status \> 70 with medical condition not contraindicating treatment with radical intent including neoadjuvant chemotherapy followed by chemoirradiation. * WBC equal or greater than 3500 mm\^3; platelet count equal or greater than 135000 mm\^3; hemoglobin equal or greater than 10 gr/L; BUN equal or less than 20; serum creatinine equal or less than 2.0. Exclusion Criteria: * Inability to undergo an MRI scan
References
Publications (0)
Data not yet available
No reference posted for this study.