Clinical trial · Interventional
Project CARE: CAncer Risk Evaluation
Project CARE: CAncer Risk Evaluation (CARE)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of Project CARE (cancer risk assessment and evaluation) research study is to explore the acceptance and feasibility of a study-initiated proactive outreach and digital care delivery model for conducting hereditary cancer risk assessment in primary care settings and facilitating genetic risk evaluation for patients flagged as high risk. Potential participants will be recruited from Rutgers Health primary care sites (family practice and general internal medicine). EPIC will be used to identify all potential participants and they will be invited to participate in the study. Consented participants will be provided a link via email, and or text message to engage with a Relational Agent (RA, chatbot), through the patient portal for cancer risk assessment and genetic education. Those identified as high risk will be offered genetic counseling and testing. The research questions the study aims to answer are: 1. What percent of patients who completed the RA are identified as high risk? 2. What percent of patients who engaged with the risk assessment were identified as high risk? 3. What percent of high-risk patients had genetic counseling or genetic testing within 4 months of completing the risk assessment?
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Care | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Relational Agent ( RA) Alex | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Feasibility and Acceptability of Relational Agent Chatbot
- interventionNames
- Behavioral: Relational Agent ( RA) Alex
Primary outcomes (2)
- measure
- Proportion of Patients Completing the Hereditary Cancer Risk Assessment
- timeFrame
- Up to 3 months from enrollment
- description
- The proportion of patients who successfully complete the hereditary cancer risk assessment within the genetic care delivery portal. Completion is defined as receiving a final result statement, regardless of whether all assessment questions in the risk assessment module were answered.
- measure
- Proportion of Patients Identified as High Risk
- timeFrame
- Through study completion, an average of 12 months.
- description
- The percent of patients who completed the RA and are identified as high risk.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria 1. Age 18 to 70 years 2. Able to read and speak English 3. Have an email address or mobile phone number in EPIC and/or are enrolled in MyChart 4. Receiving health care in Family Medicine or General Internal Medicine at Rutgers Health within the past 2 years 5. Have not opted out of receiving research-related communications 6. Have internet access (via smartphone, tablet, or computer) Exclusion Criteria 1. Dementia (e.g., Alzheimer's disease) as indicated in EPIC 2. Unable to access the Internet (via smartphone, tablet, or computer) 3. Previous germline genetic testing for hereditary cancer risk 4. Opted out of research participation in EPIC 5. Have a personal history of cancer
References
Publications (0)
Data not yet available