Clinical trial · Interventional
Impact of Different Lung Isolation Devices on Pharyngolaryngeal Injuries After Pulmonary Resection
Impact of Laryngeal Mask Combined With Visual Bronchial Blocker on Pharyngolaryngeal Injuries After Pulmonary Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to assess the impact of laryngeal mask combined with visual bronchial blocker on pharyngolaryngeal injury after pulmonary resection in patients with pulmonary nodules. The main question it aims to answer is: the incidence of postoperative pharyngolaryngeal injury within 24h : sore throat and hoarseness ? Researchers will compare the visual bronchial blocker group (VBB) with the double-lumen endotracheal tube group (DLT) to see if the visual bronchial blocker group can minimize laryngopharyngeal injury after pulmonary resection.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pulmonary Neoplasm | Lung Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| double-lumen endotracheal tube (DLT) | Device | — | UNRESOLVED |
| visual bronchial blocker (VBB) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- visual bronchial blocker group（VBB）
- description
- Laryngeal Mask Airway(LMA) size selection based on patient weight (≥70kg: size 5, 50-70kg: size 4, \<50kg: size 3)；Standard LMA insertion technique in supine position；Visual bronchial blocker inserted through LMA central channel；Blocker advancement under direct vision to identify carina
- interventionNames
- Device: visual bronchial blocker (VBB)
- type
- ACTIVE_COMPARATOR
- label
- double-lumen endotracheal tube group（DLT）
- description
- Size selection based on patient gender and height: Male: \>180cm (37F), 160-180cm (35F), \<160cm (32-35F)；Female: \>160cm (35F), \<155cm (32F), 155-160cm (individualized)；Standard laryngoscopy and DLT insertion；Fiberoptic bronchoscopy confirmation of positioning；Tracheal cuff pressure 25 cmH2O, bronchial cuff pressure 30 cmH2O
- interventionNames
- Device: double-lumen endotracheal tube (DLT)
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 years * Scheduled for elective VATS pulmonary resection under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Body mass index (BMI) 18.5-30.0 kg/m² * Written informed consent Exclusion Criteria: * Anticipated difficult airway (Mallampati class IV, previous difficult intubation, airway abnormalities) * Gastroesophageal reflux disease or gastric retention * Active pulmonary infection or bleeding * Severe pulmonary dysfunction (FEV1 \<50% predicted) * Previous lung surgery or bilateral lung surgery * Cognitive impairment affecting outcome assessment * Chronic throat pain or voice abnormalities within 24 hours preoperatively * Abnormal right upper lobe bronchial anatomy on preoperative CT for right-sided procedures * Any condition deemed unsuitable for study participation by anesthesiologist or surgeon
References
Publications (1)
- DERIVEDZhang Y, Li T, Wei J, Bao R, Lv X, Wang JF, Wu J. Laryngeal mask airway combined with visual bronchial blocker versus double-lumen tube for lung isolation in video-assisted thoracoscopic surgery: a protocol for a multicentre randomised controlled trial. BMJ Open. 2025 Dec 30;15(12):e110539. doi: 10.1136/bmjopen-2025-110539. PMID 41469076