Clinical trial · Interventional
Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
Pilot Study of Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
NCT07116161CI-TRIAL-00112943recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence in breast cancer patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT) | Other | — | UNRESOLVED |
| Graded Exercise Therapy Arm (GET) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Graded Exercise Therapy Arm (GET)
- interventionNames
- Other: Graded Exercise Therapy Arm (GET)
- type
- EXPERIMENTAL
- label
- Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)
- interventionNames
- Other: Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)
Primary outcomes (4)
- measure
- Client Satisfaction with Exercise Therapy and Cognitive Behavioural Therapy (CBT)
- timeFrame
- Up to 12 months post-enrolment.
- description
- Measured using a 8-item Client Satisfaction Questionnaire. Each item is rated on a 4-point scale, with higher scores indicating greater satisfaction.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: Primary cohort (N=90): 1. Female 2. ≥21 years of age 3. Stage I-III breast cancer regardless of hormone receptor status or human epidermal growth factor receptor 2 (HER2) status 4. Completed surgery 5. Completed adjuvant chemotherapy, if indicated 6. Reported fatigue (One-item fatigue scale score ≥ 4) 7. Ability to read and communicate in English 8. Willing to provide informed consent for the study participation Exploratory cohort (N=10): 1. Female 2. ≥21 years of age 3. Stage IV breast cancer regardless of hormone receptor status or human epidermal growth factor receptor 2 (HER2) status 4. Completed surgery 5. Currently receiving systemic therapy (e.g. endocrine therapy, chemotherapy, targeted therapy or immunotherapy) 6. Reported fatigue (One-item fatigue scale score ≥ 4) 7. Ability to read and communicate in English 8. Willing to provide informed consent for the study participation Exclusion Criteria for both cohorts: 1. Pregnant or lactating 2. Presence of dementia or major psychiatric disease 3. Deemed medically unsuitable by medical team for low to moderate intensity exercise 4. Unable or unwilling for tele-counselling sessions 5. Uncontrolled pain or undiagnosed pain 6. Low blood counts: Hb \<8.0, Platelet \<50K, ANC \<1 7. Electrolyte imbalances: K \<3.0, Na \<130 8. Cardiovascular diseases, including but not limited to: LVEF \<35%, uncontrolled arrhythmias, severe coronary artery disease, severe valvular heart disease, uncontrolled hypertension etc. not cleared by a cardiologist 9. Active infection 10. Currently engaged in moderate to vigorous physical activity
References
Publications (0)
Data not yet available
No reference posted for this study.