Clinical trial · Interventional
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
A Randomized Controlled Pilot Trial of a Behavioral Intervention to Increase Uptake of Genetic Services Among Relatives at Risk of Lynch Syndrome
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services. Untested relatives of patients with Lynch syndrome will be recruited to complete a baseline survey and will be randomized to receive either the an information letter or an information letter plus a booklet. Two follow-up surveys will be administered over the span of 6 months. Participants will also be invited to join an optional exit interview to provide feedback.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Prevention | — | UNRESOLVED | — |
| Cascade Testing | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Decision Making | — | UNRESOLVED | — |
| Lynch Syndrome | — | UNRESOLVED | — |
| Uterine Cancer | Malignant Uterine Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Information Letter | Behavioral | — | UNRESOLVED |
| Information Letter and Booklet | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Information Letter
- description
- This arm provides an information letter about Lynch syndrome and genetic services.
- interventionNames
- Behavioral: Information Letter
- type
- EXPERIMENTAL
- label
- Information Letter and Booklet
- description
- This arm provides an information letter with a booklet about Lynch syndrome and genetic services.
- interventionNames
- Behavioral: Information Letter and Booklet
Primary outcomes (3)
- measure
- Feasibility (recruitment and retention rates, completeness of assessment data)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Probands Inclusion Criteria: * English speaking * at least 18 years old * have had genetic testing for Lynch syndrome (LS) * do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening) Clinical Trial Participants Inclusion Criteria: * English-speaking * at least 18 years old * a blood relative of a patient who was diagnosed with LS * potentially at risk for LS * have not scheduled or had pre-test genetic counseling or genetic testing for LS * do not have a personal history of a cancer (excluding non-melanoma skin cancer) * do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)
References
Publications (0)
Data not yet available