Clinical trial · Observational
Compairing R-ICNB and C-ICNB for Postoperative Pain Management After Minimal-invasive Anatomical Lung Resection
A Randomized Pilot Study of ICNB With Ropivacaine Versus ICNB With Cryotherapy for Postoperative Pain Management After RATS Anatomical Resection for Lung Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a pilot study in which a total of 6 people will participate. This study aims to optimize the postoperative pain management of an anatomically minimally invasive lung resection (RATS) by comparing 2 pain-relieving techniques. As standard, an intercostal block is placed at the end of the procedure by injecting a local anesthetic at the site where the patient will be operated on. This study compares the previous method with the use of cryotherapy as an intercostal block. This technique uses cryo probes and blocks postoperative pain for 1-3 months. By comparing both techniques, it is examined whether cryotherapy requires less pain medication and is therefore more effective.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Postoperative Pain Management | — | UNRESOLVED | — |
| RATS Surgery | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- R-ICNB
- description
- At the end of the procedure, an intercostal block is placed by injecting a local anesthetic into the site of surgery.
- label
- C-ICNB
- description
- At the end of the surgery single shot cryotherapy will be placed at 6 levels (T3-T8) with the AtriCure"s cryoICE cryosphere cryoablation probes.
Primary outcomes (1)
- measure
- The NRS pain score
- timeFrame
- Baseline, post-operative (day 0) in the recoveryward when the patient is awake and after 6 hours. Day 1-2-3 the NRS wil be measured in the morning, afternoon and evening. During the Follow-up visits: 2 weeks and 12 weeks after surgery
- description
- The NRS score will be used to measure pain scores and this will be the primary outcome of the study.
Secondary outcomes (8)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Adult patients of 18 years or older who are able to give informed consent and fill out questionnaires in Dutch. Exclusion Criteria: * Patients who need an anatomic resection of the lung that's larger than one lung lobe, who have CPAM or infections. * Patients with chronic use (\>3 months) of strong opioids because of co-morbidities -for example, the use of tramadol is allowed. * If there's a high risk of conversion to a thoracotomy. This will be evaluated by the lung surgeon. * Patients who have had thoracic surgery in the past. * Patients with chronic kidney disease stage 4 or 5 (GFR \< 30 mL/min)
References
Publications (0)
Data not yet available