Clinical trial · Observational
Additional Prognostic Value of Tumor Grade Beyond the 21-gene Recurrence Score
Prognostic Implication of Tumor Grade in Patients With Node-negative Breast Cancer Aged ≤ 50 Years With 21-gene Recurrence Scores of 11-25
NCT07093775CI-TRIAL-00092830not yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluated the prognostic significance of tumor grade in patients with node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2-negative breast cancers treated according to RS-guided strategies.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Tumor Grade | Breast Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tumor grade (I or II vs. III) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Recurrence-free interval
- timeFrame
- through study completion, an average of 5 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with hormone receptor-positive, HER2-negative early-stage breast cancer * Patients treated between January 2011 and December 2023 * Patients with available clinicopathologic data and 21-gene Oncotype DX assay results confirmed through electronic medical records Exclusion Criteria: * Patients with breast cancer under the age of 20 * Patients diagnosed with stage IV breast cancer * Patients for whom clinicopathologic data cannot be retrieved from electronic medical records
References
Publications (0)
Data not yet available
No reference posted for this study.