Clinical trial · Interventional
Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional Recovery
Enhancing Functional Recovery With Home-based Transcranial Direct Current Stimulation (tDCS) in Patients With Stroke, Neurodegeneration and Brain Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the feasibility of home-based Transcranial Direct Current Stimulation (tDCS) combined with a home activity based therapy program in patients with stroke, brain tumors or neurodegenerative conditions and to assess the efficacy of home-based tDCS combined with a home activity-based therapy program as an intervention to treat cognitive-linguistic impairments related to stroke, brain tumors, or neurodegenerative conditions and improve quality of life.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Neurodegeneration | — | UNRESOLVED | — |
| Stroke | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cognitive-linguistic therapy | Behavioral | — | UNRESOLVED |
| Soterix® tDCS - Home treatment | Device | — | UNRESOLVED |
| Soterix® tDCS - Lab treatment | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Home-Based Treatment: Active Stimulation, Then Sham Stimulation
- description
- Subjects will first receive active tDCS, plus home activity based cognitive-linguistic therapy then they will cross over to the home-based sham treatment arm after a 4-8-week washout period.
- interventionNames
- Device: Soterix® tDCS - Home treatment
- Behavioral: Cognitive-linguistic therapy
- type
- EXPERIMENTAL
- label
- Home-Based Treatment: Sham Stimulation, Then Active Stimulation
- description
- Subjects will first receive sham tDCS, plus home activity based cognitive-linguistic therapy then they will cross over to the home-based active treatment arm after a 4-8-week washout period.
- interventionNames
- Device: Soterix® tDCS - Home treatment
- Behavioral: Cognitive-linguistic therapy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * At least 3 months after ischemic/hemorrhagic/anoxic stroke or 3 months after completion of cranial radiation or cranial surgery for treatment of primary or metastatic intracranial tumors or neurodegenerative conditions include, but are not limited to, primary progressive aphasia, corticobasal syndrome, progressive supranuclear palsy, Parkinson's disease, and Alzheimer's disease dementia. * Expected survival \>6 months * Functional impairment in the domains of language and/or cognition affecting quality of life determined by PI. * Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia). * Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia). Exclusion Criteria: * Pregnancy * Contraindication to tDCS, including metallic implanted objects. * Medical instability or inability to cooperate during the study as assessed by the treating physician to participate in the study. * Individuals with epilepsy
References
Publications (0)
Data not yet available