Clinical trial · Interventional
Virtual Reality Meditation on Anxiety in Cancer Patients Receiving Chemotherapy
The Effect of Virtual Reality Meditation on Anxiety Management in Cancer Patients Receiving Chemotherapy: A Randomized Controlled Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main questions this study aims to answer are: Does VR meditation, delivered through virtual reality glasses and the MediboothVR application, effectively reduce anxiety in cancer patients during chemotherapy? Is there a meaningful difference in anxiety reduction between the VR intervention groups and the control group? Researchers will compare two intervention groups using VR glasses-one with guided meditation and one with calming video content-to a control group receiving standard care, to see if there are differences in anxiety levels. Participants will: Be randomly assigned to one of three groups Attend their scheduled chemotherapy sessions Depending on group assignment, either: Use VR glasses with the MediboothVR meditation app for 10 minutes daily Use VR glasses to watch calming 360-degree nature videos for 10 minutes daily Receive standard care with no VR use All participants will complete anxiety questionnaires and have their vital signs recorded before and after each session.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Virtual reality meditation | Behavioral | — | UNRESOLVED |
| Virtual Reality Videos | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Virtual reality meditation group
- description
- Participants in this group will use a virtual reality (VR) headset to complete a 10-minute meditation session on three consecutive days. A different meditation video will be used each day, and sessions will be held between 10:00 AM and 12:00 PM. The meditation sessions are provided through the "MediboothVR" application. This app is the first immersive virtual reality meditation tool developed in Türkiye and supports the Turkish language. In MediboothVR, participants experience a 360-degree guided meditation in a virtual environment. Each video starts with a short environmental scene, followed by a visual journey to a meditation space where a guiding silhouette appears and leads the participant through the session. Each session lasts approximately 10 minutes.
- interventionNames
- Behavioral: Virtual reality meditation
- type
- ACTIVE_COMPARATOR
- label
- Virtual Reality Video Group
- description
- This group will use a VR headset on three consecutive days between 10:00 AM and 12:00 PM. Instead of meditation, participants will watch 360-degree nature videos. A different video (10 minute) will be shown each day. The purpose is to create a calming, immersive experience without guided meditation.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 18 years or older, * Sufficient communication ability to respond to study questions, * Receiving outpatient treatment for at least three consecutive days with a confirmed cancer diagnosis, * Scoring 40 or above on the State Anxiety Inventory (STAI-S), indicating moderate or higher anxiety levels, * Voluntarily agreeing to participate in the study. Exclusion Criteria: * Inability to speak or understand Turkish, * Being under contact isolation precautions, * Presence of active eye discharge or visual impairment, * History of seizures, epilepsy, or hypersensitivity to flashing lights, * History of vertigo or motion sickness, * Experiencing active nausea or vomiting, * Having wounds or dressings on the head or face that interfere with the use of a VR headset, * Hearing impairment, * Hypersensitivity of the face or scalp to light pressure, * Diagnosis of psychiatric conditions that may affect participation (e.g., schizophrenia, severe psychosis), * Diagnosis of recurrent or relapsed cancer, * Scoring below 40 on the State Anxiety Inventory, * Previous use of virtual reality applications, * Prior experience with meditation practices.
References
Publications (4)
- BACKGROUNDUslu A, Arslan S. The Effect of Using Virtual Reality Glasses on Anxiety and Fatigue in Women with Breast Cancer Receiving Adjuvant Chemotherapy: A Pretest-Posttest Randomized Controlled Study. Semin Oncol Nurs. 2023 Oct;39(5):151503. doi: 10.1016/j.soncn.2023.151503. Epub 2023 Sep 22. PMID 37741768
- BACKGROUNDFranklin, D. M., Silvestro, C., Carrillo, R. A., Yang, Y., Annadurai, D., Ganesan, S., Vasantham, D. S. J., Mettu, S., Patel, M., Patil, M. S., & Akurathi, N. D. (2023). The impact of meditation aided by VR technology as an emerging therapeutic to ease cancer related anxiety, stress, and fatigue. Frontiers in Virtual Reality, 4(July), 1-12. https://doi.org/10.3389/frvir.2023.1195196
- BACKGROUNDWu Y, Wang N, Zhang H, Sun X, Wang Y, Zhang Y. Effectiveness of Virtual Reality in Symptom Management of Cancer Patients: A Systematic Review and Meta-Analysis. J Pain Symptom Manage. 2023 May;65(5):e467-e482. doi: 10.1016/j.jpainsymman.2023.01.023. Epub 2023 Feb 8. PMID 36758907
- BACKGROUNDChow H, Hon J, Chua W, Chuan A. Effect of Virtual Reality Therapy in Reducing Pain and Anxiety for Cancer-Related Medical Procedures: A Systematic Narrative Review. J Pain Symptom Manage. 2021 Feb;61(2):384-394. doi: 10.1016/j.jpainsymman.2020.08.016. Epub 2020 Aug 19. PMID 32822755