Clinical trial · Observational
Precision Performance Status Compared With ECOG Performance Status
Precision Performance Status Compared With ECOG Performance Status- A Pilot Cross Sectional Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study is not progressing towards scientific goals
Summary
Brief summary (as posted)
This study compares consumer movement trackers to the Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) in monitoring cancer patient movement. The ECOG PS emphasizes a patient's ambulatory status (ability to walk around), and scores patients on a scale of 0-5: 0 (no restrictions), 1 (ambulatory), 2 (\< 50% of hours spent in bed, unable to carry out work activities), 3 (\> 50% of hours spent in bed, limited in self care), 4 (bedbound and gravely disabled) and 5 (deceased). Accurate assessment of a patient's PS is paramount in informing therapeutic decision-making, whether it be to predict response and tolerability to treatment or determine eligibility for clinical trials. However, the ECOG PS scale is observational, and therefore limited in its precision. Information gained in this study may help researchers learn if there is a better way to assess patient movement with computerized analysis tools using movement trackers.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematopoietic and Lymphatic System Neoplasm | Hematopoietic and Lymphatic System Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Malignant Solid Neoplasm | Malignant Solid Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Functional Assessment | Other | — | UNRESOLVED |
| Timed Get Up and Go Test | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational ("Get Up and Go" and chair-to-table assessments)
- description
- Patients undergo "Get Up and Go" assessment as well as a chair-to-table assessment during the clinic visit on study.
- interventionNames
- Other: Functional Assessment
- Behavioral: Timed Get Up and Go Test
Primary outcomes (1)
- measure
- Median acceleration at the Spine Base and non-pivoting leg
- timeFrame
- Day 1
- description
- The Kinect device will record the participant performing the chair to examination table activity and the Get up and Go activity. This recording will quantify spine and non-pivoting leg mean acceleration during movement onto an examination table and the Get up and Go time. These values will be assessed for a linear or monotonic relationship with Eastern Cooperative Oncology Group (ECOG) scores. If a linear relationship is exhibited the primary objective will be evaluated via a Pearson correlation coefficient. However, the supposition is the data will more likely reflect a monotonic relationship. In this event the primary objective will be evaluated via a Kendall Rank Tau-b correlation coefficient.
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * A diagnosis of cancer * Age \>= 18 years * Ability to understand and the willingness to sign a written informed consent * Able to ambulate without an assistive device Exclusion Criteria: * Missing lower limbs * Known movement disorder such as Parkinson's disease, choreoathetoid movement disorders, essential tremor if that movement disorder is of sufficient severity to require drug therapy
References
Publications (1)
- DERIVEDWang C, Prasad A, Qi E, Pai J, Law J, Chennapan K, Jirka G, Kuhn P, Tale M, Nocera L, Nieva J. Augmenting Performance Status: A Preliminary Study of Objective Kinematic Assessment Using Motion Capture. Oncol Ther. 2026 Jun;14(2):735-747. doi: 10.1007/s40487-026-00434-x. Epub 2026 May 7. PMID 42098537