Clinical trial · Observational
Intraoperative Pathologic Evaluation of Central Lymph Nodes in Papillary Thyroid Carcinoma
Intraoperative Pathologic Evaluation of Central Lymph Nodes to Determine the Extent of Surgery in Papillary Thyroid Carcinoma : A Retrospective Cohort Study
NCT07066644CI-TRIAL-00092338completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Efficacy of Intraoperative pathologic evaluation of central lymph nodes
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer, Papillary | Thyroid Gland Papillary Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| central node dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- the accuracy of IOPE
- timeFrame
- Perioperative
- description
- To evaluate IOPE accuracy, the findings were compared with the final pathology results, utilizing key parameters such as sensitivity, specificity, false-negative rate (FNR), and false-positive rate for analysis.
Secondary outcomes (2)
- measure
- the incidence of complications in IOPE [safety of IOPE]
- timeFrame
- up to 6 months
- description
- The safety was evaluated by examining the incidence of complications, including vocal cord palsy and hypoparathyroidism. vocal cord palsy : measured by laryngeal sono hypoparathyroidism : serum parathyroid hormone levels \< 15.0 pg/mL
- measure
- the risk factors for central lymph node metastasis
- timeFrame
- perioperative
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * patients with unilateral papillary thyroid cancer * no evidence of lymph node metastasis (clinically N0) * performed with Intraoperative pathologic evaluation Exclusion Criteria: * those with a history of neck surgery * those with lateral lymph node metastasis * those with suspected extrathyroidal extension * those in whom Intraoperative pathologic evaluation was not performed
References
Publications (2)
- RESULTAhn BH, Kim JR, Jeong HC, Lee JS, Chang ES, Kim YH. Predictive factors of central lymph node metastasis in papillary thyroid carcinoma. Ann Surg Treat Res. 2015 Feb;88(2):63-8. doi: 10.4174/astr.2015.88.2.63. Epub 2015 Jan 27. PMID 25692116
- RESULTBae HL, Ahn JH, Kwak J, Kim HS, Yoon SG, Yi JW, Kim SJ, Lee KE. Intraoperative pathologic evaluation of central compartment lymph nodes in patients undergoing lobectomy for unilateral papillary thyroid carcinoma. Asian J Surg. 2024 Jan;47(1):360-366. doi: 10.1016/j.asjsur.2023.08.203. Epub 2023 Oct 25. PMID 37891110