Clinical trial · Interventional
Tubeless VATS for Mediastinal Neoplasm
A Randomized Controlled Trial of Non-intubated Versus Intubated VATS for Mediastinal Neoplasm
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mediastinal Neoplasm | Mediastinal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Non-intubated Anesthesia | — | UNRESOLVED | — |
| Tubeless | — | UNRESOLVED | — |
| VATS | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intubated VATS for mediastinal neoplasm | Procedure | — | UNRESOLVED |
| Non-intubated VATS for mediastinal neoplasm | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Non-intubated group
- description
- Patients received tubeless VATS for mediastinal neoplasm
- interventionNames
- Procedure: Non-intubated VATS for mediastinal neoplasm
- type
- ACTIVE_COMPARATOR
- label
- Intubated group
- description
- Patients received VATS mediastinal neoplasm resection under intubated general anesthesia.
- interventionNames
- Procedure: Intubated VATS for mediastinal neoplasm
Primary outcomes (3)
- measure
- Conversion rate to open surgery
- timeFrame
- postoperative in-hospital stay up to 30 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Mediastinal neoplasm was diagnosed by chest enhanced CT 2. The patients with age ≥ 18 and ≤ 80 years old 3. The patients whose tumor diameter was \<6 cm 4. ASA grade: I-III 5. The patients should understand the research and sign the informed consent Exclusion Criteria: 1. Imaging examinations revealed that the tumor had invaded adjacent organs, with evidence of pleural or pericardial dissemination, as well as lymphatic and/or hematogenous metastases 2. Patients with a confirmed history of congestive heart failure, poorly controlled angina despite medical therapy, electrocardiogram-confirmed myocardial infarction with transmural involvement, uncontrolled hypertension, clinically significant valvular heart disease, or high-risk arrhythmias not adequately managed 3. Patients with concurrent active malignancies
References
Publications (0)
Data not yet available