Clinical trial · Interventional
Standardized Resistance Training Program and Assessment System for Prostate Cancer Patients Receiving Androgen Deprivation Therapy ISPoRT-PCa-ADT Study Protocol for a Randomized Controlled Trial. SPORT-MU
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled trial (RCT) with two parallel study arms evaluated the effectiveness of a 24-week exercise intervention in prostate cancer (PCa) patients under-going androgen deprivation therapy (ADT). Ethical approval was obtained from the Clinical Research Ethics Committee of the University Clinical Hospital "Virgen de la Arrixaca" (Murcia, Spain). Participants were randomly assigned to one of two groups: (1) a supervised progressive resistance training program (SPoRT-PCa-ADT), or (2) a control group receiving a home-based exercise protocol following an initial assessment, accom-panied by weekly telephone follow-up. Assessments were conducted at baseline and at 24 weeks to examine changes in physical, functional, and psychosocial outcomes. Addi-tionally, patient-reported outcomes were collected at the 12-week midpoint (Figure 1). This study design enabled the evaluation of both immediate and sustained intervention effects and facilitated a direct comparison between supervised and home-based exercise approaches
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise Intervention Protocol | Procedure | — | UNRESOLVED |
| SPoRT-Control Intervention | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- SPORT Protocol intervention
- description
- 24 week velocity based resistance training. Twice weekly supervised sessions
- interventionNames
- Procedure: SPoRT-Control Intervention
- type
- ACTIVE_COMPARATOR
- label
- SPORT Control intervention
- description
- 24-week home based resistance training program .
- interventionNames
- Procedure: Exercise Intervention Protocol
Primary outcomes (8)
- measure
- Progressive loading test
- timeFrame
- Up for a 24 weeks
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosis of locally advanced or metastatic prostate neoplasm and current treatment with androgen deprivation therapy (ADT) * treatment at the radiotherapy oncology department of University Clinical Hospital "Virgen de la Arrixaca" * legal adult age with signed informed consent Exclusion Criteria: * unwillingness to participate in the study * inability to complete adequate follow-up due to any cause that would prevent knowledge of patient evolution during the follow-up period * no controlled or symptomatic metastatic bone disease * physical disabilities that would prevent participants from safely completing the exercise protocol
References
Publications (1)
- DERIVEDSoler-Lopez A, Gomez-Carmona CD, Gonzalez-Devesa D, Lopez-Plaza D, Herrero-Vidal L, Toledo-Pozuelo R, Gonzalez-Costea A, Cao-Avellaneda E. Standardized Program of Resistance Training for Prostate Cancer Patients Receiving Androgen Deprivation Therapy (SPoRT-PCa-ADT): study protocol for a randomized controlled trial. BMC Cancer. 2026 Apr 22;26(1):711. doi: 10.1186/s12885-026-15902-w. PMID 42015017