Clinical trial · Interventional
Evidence-Based Nursing for Fatigue and Quality of Life in Lung Cancer Chemotherapy
Effects of Evidence-Based Nursing Under a Quantitative Assessment Strategy on Cancer-Related Fatigue, Self-Management Ability, and Quality of Life in Lung Cancer Patients Undergoing Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective randomized controlled trial investigated the effects of an evidence-based nursing intervention under a quantitative assessment strategy (EB-NQAS), utilizing the Edmonton Symptom Assessment Scale (ESAS), on cancer-related fatigue, self-management ability, and quality of life in lung cancer patients undergoing chemotherapy. Outcomes were compared to a group receiving routine nursing care.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Evidence-Based Nursing Under Quantitative Assessment Strategy (EB-NQAS) | Behavioral | — | UNRESOLVED |
| Routine Nursing Care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Evidence-Based Nursing Under Quantitative Assessment Strategy (EB-NQAS) Group
- description
- Participants (n=75) received evidence-based nursing under a quantitative assessment strategy. This involved baseline assessment with ESAS; tailored care planning for pain, fatigue, nausea/vomiting, and psychological distress (including CBT, activity/sleep plans, prophylactic antiemetics); and dynamic daily/weekly evaluation and adjustment of care based on ESAS scores.
- interventionNames
- Behavioral: Evidence-Based Nursing Under Quantitative Assessment Strategy (EB-NQAS)
- type
- ACTIVE_COMPARATOR
- label
- Routine Nursing Care Group
- description
- Participants (n=75) received standard nursing care as per hospital guidelines, including health education on lung cancer and chemotherapy, weekly 15-minute psychological support sessions, individualized dietary guidance, and verbal instructions on managing adverse effects.
- interventionNames
- Behavioral: Routine Nursing Care
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Pathologically or radiologically confirmed lung cancer (World Health Organization \[WHO\] 2021 diagnostic criteria). * Scheduled to receive first-line chemotherapy (platinum-based regimen). * Karnofsky Performance Status (KPS) score ≥60. * Estimated survival time \>6 months (assessed by treating oncologist). * Normal mental and cognitive function (Mini-Mental State Examination \[MMSE\] score ≥24). * Voluntary participation and signed informed consent. Exclusion Criteria: * Concurrent severe organ dysfunction (Child-Pugh score ≥B for liver; estimated glomerular filtration rate \[eGFR\] \<30 mL/min/1.73m² for kidney). * Active neurological disorders (e.g., stroke, epilepsy) affecting symptom reporting. * Acute infectious diseases (e.g., tuberculosis with sputum positivity). * Known allergies to chemotherapy drugs (e.g., platinum agents). * Acute illnesses requiring hospitalization (e.g., pneumonia, myocardial infarction). * Secondary malignancies (pathologically confirmed). * Chemotherapy contraindications (e.g., uncontrolled heart failure). * Inability to communicate in the local language (assessed via nurse interview). * Concurrent radiotherapy or immunotherapy. * Participation in other interventional clinical trials within 3 months.
References
Publications (0)
Data not yet available