Clinical trial · Observational
Clinicopathological Value of p16 Expression in Colorectal Carcinoma
Clinicopathological Value of p16 Expression in Colorectal Carcinoma: An Immunohistochemical Study.
NCT07047482CI-TRIAL-00091991recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of the immunohistochemical expression of p16 in colorectal carcinoma and correlate its expression to different clinical and pathological parameters as patients' ages, sexes, tumor location, histopathological phenotype, status of nodal involvement, perineural and lymphovascular invasion.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Carcinoma | Colorectal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Immunohistochemical staining | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Participants
- description
- Fifty (50) cases of colorectal cancer will be performed from archieved formalin-fixed, paraffin-embedded tissue blocks referred to Pathology Department, Sohag University Hospitals.
- interventionNames
- Biological: Immunohistochemical staining
Primary outcomes (1)
- measure
- Evaluation of p16 Expression in Colorectal Carcinoma.
- timeFrame
- 6 months
- description
- Immunohistochemical staining of Colorectal tissues by p16 monoclonal antibody
Secondary outcomes (1)
- measure
- Correlation of p16 expression to different clinical and pathological parameters
- timeFrame
- 6 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Specimens from patients with colorectal cancer. 2. Tissue blocks with sufficient material. 3. Specimens with sufficient clinical data. Exclusion Criteria: 1. Tissue blocks with insufficient, destroyed or necrotic material. 2. Specimens with insufficient clinical data.
References
Publications (0)
Data not yet available
No reference posted for this study.