Clinical trial · Interventional
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
A Randomized Controlled Double-blinded Trial Evaluating the Efficacy of the Anterior Quadratus Lumborum Block as a Component of Multimodal Perioperative Analgesia for Abdominal Hysterectomies
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after abdominal hysterectomy and improve quality of recovery after anesthesia. The study hypothesis is that anterior QL block bilaterally before the start of a surgery has no impact on perioperative pain relief, can't reduce the need in opioids and will not improve quality of recovery after anesthesia. All patients will undergo general anesthesia with tracheal intubation and mechanical ventilation. Patients will be randomized into two groups. In addition to general anesthesia and multimodal analgesia with parenteral medication II (QL) group will receive also anterior quadratus lumborum block as a regional component.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Uterine Bleeding | — | UNRESOLVED | — |
| Uterine Diseases | — | UNRESOLVED | — |
| Uterine Fibroids | Uterine Corpus Leiomyoma | ALIAS | 0.90 |
| Uterine Neoplasms | Uterine Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ANTERİOR QUADRATUS LUMBORUM BLOCK | Procedure | — | UNRESOLVED |
| General Anesthesia (GA) | Procedure | — | UNRESOLVED |
| Parenteral administration of analgesics | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group I (control)
- description
- Patients in Group I will undergo general anesthesia with tracheal intubation and mechanical ventilation. Analgesia regimen will include parenteral medication.
- interventionNames
- Drug: Parenteral administration of analgesics
- Procedure: General Anesthesia (GA)
- type
- EXPERIMENTAL
- label
- Group II (QL)
- description
- Patients in Group II (QL) will undergo general anesthesia with tracheal intubation and mechanical ventilation. Analgesia regimen will include parenteral medication and anterior quadratus lumborum block as a regional component.
- interventionNames
- Procedure: ANTERİOR QUADRATUS LUMBORUM BLOCK
- Drug: Parenteral administration of analgesics
- Procedure: General Anesthesia (GA)
Primary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * patients with ASA status I-II * patients with symptomatic fibroids * patients scheduled for abdominl hysterectomy Exclusion Criteria: * refusal to participate in the study at any of its stages * ASA class ≥ III * body mass index \> 40 kg/m2 * use of opiate receptor agonists/antagonists before surgery * uncontrolled hypertension
References
Publications (0)
Data not yet available