Clinical trial · Interventional
Molecular and Cellular Profiling of Uterine Lavage Collected During Gynecologic Surgery
Exploring the Molecular and Cellular Composition of Uterine Lavage Specimens Collected at the Time of Gynecologic Surgery.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is a designed as a to test the clinical and technical feasibility of using this novel uterine lavage collection catheter to collected UL samples from up to 50 individuals undergoing gynecologic surgery and to describe the cellular composition of these samples. In order to do this, it is a prospective consecutively-enrolled cohort of 50 participants, all of who will receive the intervention of uterine lavage collection.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gynecological Surgery | — | UNRESOLVED | — |
| Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | ALIAS | 0.90 |
| Gynecologic Disease | — | UNRESOLVED | — |
| Uterine Cancer | Malignant Uterine Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Uterine Lavage | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Single Group
- description
- Participants undergoing gynecologic surgery who agree to uterine lavage collection intraoperatively for molecular and cellular analysis.
- interventionNames
- Procedure: Uterine Lavage
Primary outcomes (1)
- measure
- Characterization of cellular composition in uterine lavage fluid
- timeFrame
- At time of gynecologic surgery
- description
- Quantification and classification of cell types obtained from uterine lavage specimens using cytology and/or flow cytometry.
Secondary outcomes (2)
- measure
- Molecular profiling of uterine lavage specimens
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Undergoing gynecologic surgery with Stanford Healthcare * Intact uterus and cervix * At least one intact fallopian tube and ovary (on the same side) * Aged 18 years or older * Ability to understand and the willingness to provide written informed consent. Exclusion Criteria: * Known endometrial or cervical cancer or endometrial or cervical intraepithelial neoplasia * Status post bilateral salpingectomy or tubal ligation * Lack of consenting capacity * Positive preoperative pregnancy test * Active uterine bleeding (i.e. menses, etc.) * Intrauterine device in place * Non-English speaking (requires interpretor)
References
Publications (0)
Data not yet available