Clinical trial · Interventional
When to Block? Timing of Scalp Block in Craniotomy
Scalp Block Before Head Pinning or Before Emergence in Supratentorial Tumor Craniotomy: A Randomized Controlled Evaluation of Quality of Recovery and Hemodynamic Responses
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate the effect of scalp block timing-Group 1 will receive a pre-pinning scalp block, while Group 2 will receive a pre-emergence scalp block.-on postoperative recovery quality in patients undergoing supratentorial tumor craniotomy. The recovery quality will be assessed using the validated Quality of Recovery-40 (QoR-40) questionnaire. A total of 60 patients, aged 18-80 years, classified as ASA I-III and with a Glasgow Coma Scale (GCS) score of 15 upon admission to the recovery unit, will be enrolled. The primary outcome is the QoR-40 score. Secondary outcomes include hemodynamic changes and pain intensity measured by the Visual Analog Scale (VAS).
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Craniotomy Surgery | — | UNRESOLVED | — |
| QoR-40 | — | UNRESOLVED | — |
| Regional Anesthesia | — | UNRESOLVED | — |
| Scalp Block | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pre-emergence Group | Procedure | — | UNRESOLVED |
| pre-pinning group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- pre-pinning group
- description
- Patients in this group will receive a scalp block with 0.25% bupivacaine (20 mL) after the induction of general anesthesia but prior to head pinning
- interventionNames
- Procedure: pre-pinning group
- type
- ACTIVE_COMPARATOR
- label
- pre-emergence Group
- description
- Patients in this group will receive a scalp block with 0.25% bupivacaine (20 mL) at the end of surgery, before emergence from anesthesia.
- interventionNames
- Procedure: pre-emergence Group
Primary outcomes (1)
- measure
- Quality of Recovery Score
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged between 18 and 80 years. * Scheduled for elective supratentorial tumor craniotomy under general anesthesia * ASA physical status classification I to III. * Glasgow Coma Scale (GCS) score of 15 at the time of emergence from anesthesia. * Provide informed consent to participate in the study. Exclusion Criteria: * Chronic use of analgesic medications prior to surgery. * Glasgow Coma Scale (GCS) score below 15 postoperatively. * Allergy or hypersensitivity to local anesthetics or opioids used in the study. * Contraindications for scalp block or patient-controlled analgesia. * Patients with severe hepatic, renal, or cardiac dysfunction. * Patients unable to comprehend or complete the QoR-40 questionnaire.
References
Publications (0)
Data not yet available