Clinical trial · Observational
Efficacy and Safety of Surgical Treatment for Type IVa CBD
The Efficacy and Safety of Surgical Treatment in Type IVa Congenital Biliary Dilation: A Multi-center Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is a multicenter, bidirectional cohort study aimed at continuously enrolling patients with biliary dilatation from 25 medical centers in China. It will collect comprehensive life-cycle data from the cohort to establish a Chinese cohort for IVa biliary dilatation (BD). Based on this cohort, the study seeks to compare the perioperative risks, long-term outcomes, and quality of life of type IVa BD following surgical treatment, to establish standardized surgical treatment strategies for type IVa BD.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Choledochal Cyst | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Liver Resection Group
- description
- This group included patients with type IVa BD who underwent liver resection, extrahepatic bile duct resection and Roux-en-Y hepaticojejunostomy
- label
- Hepaticojejunostomy Group
- description
- This group included patients with type IVa BD who underwent extrahepatic bile duct resection and Roux-en-Y hepaticojejunostomy
Primary outcomes (1)
- measure
- Long-term complication-free survival (LCFS)
- timeFrame
- After 30 or 90 days of surgery
- description
- For patients who have undergone surgical treatment, the occurrences of long-term postoperative complications include recurrent cholangitis, intrahepatic bile duct stones, stenosis of the bilioenteric anastomosis, and other such conditions
Secondary outcomes (5)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients who have been diagnosed with Todani type IVa BD. 2. Patients aged between 0 and 80 years old, regardless of gender. 3. First-time receipt of surgery. Exclusion Criteria: 1. With abnormal intrapancreatic bile duct 2. Inappropriate Roux-loop length (outside the range of 40-60 cm for adults and 15-30 cm for children) 3. With non-relevant surgical interventions 4. Pathologically confirmed carcinogenesis 5. Unresolved choledocholithiasis, bile duct stenosis, and Intrahepatic bile duct stones during the procedure. 6. Unavailable follow-up information.
References
Publications (0)
Data not yet available