Clinical trial · Observational
Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
EXERT-BCHC: Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 5/5/5 Cluster Set Training Regimen | Other | — | UNRESOLVED |
| 6-12-25 Training Regimen | Other | — | UNRESOLVED |
| 8x8 Training Regimen | Other | — | UNRESOLVED |
| Double Training Regimen | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Change in VO2 max
- timeFrame
- Measured monthly during the 5-month exercise program at weeks 4, 8, 12, 16, and 20.
- description
- Change in maximal oxygen consumption (VO2 max) measured during and after each exercise regimen.
- measure
- Change in Muscle and Fat Mass
- timeFrame
- Baseline, at the completion of the 5-month exercise program (Week 20), and monthly during the exercise program at weeks 4, 8, 12, and 16.
- description
- Change in muscle mass and fat mass in pounds as measured by InBody 970.
- measure
- Change in Muscle and Fat Mass
- timeFrame
- Baseline, at the completion of the 5-month exercise program (Week 20), and monthly during the exercise program at weeks 4, 8, 12, and 16.
- description
- Change in muscle mass and fat mass in pounds as measured by ultrasound.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age 20-89 years 2. Women prescribed exercise as a Standard of Care 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. 5. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed. 6. Women with \> 6 months of resistance training experience under expert guidance by a CSCS Exclusion Criteria: 1. Any current treatment with cytotoxic chemotherapy for breast cancer 2. Inability to safely engage in group sessions of resistance training as deemed by study Pl 3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by Pl to be unsafe to engage in resistance training 4. Beta blocker or GLP-1 inhibitor medications 5. Pregnant women 6. Males
References
Publications (0)
Data not yet available