Clinical trial · Observational
AI-Driven Precision Diagnostic System for Lung Cancer Based on Liquid Biopsy
Retrospective Clinical Study for Developing an AI-Driven Precision Diagnostic System for Lung Cancer Based on Liquid Biopsy
NCT07009769CI-TRIAL-00090758completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators aim to develop an AI-powered precision medicine system based on liquid biopsy that can comprehensively provide lung cancer patients with information on disease stage, histologic subtype, and presence of genetic mutations.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Diagnostic accuracy of the AI-based classification model using SERS signals from plasma-derived exosomes
- timeFrame
- Retrospective, based on pre-collected samples through study completion, an average of 1 year
- description
- To evaluate the diagnostic performance (sensitivity, specificity, and overall accuracy) of a machine learning model trained on SERS spectral data of plasma-derived exosomes in distinguishing lung cancer patients from healthy controls.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria (Patients) * Republic of Korea nationality * Age ≥ 30 years * Lung cancer based on radiologic and/or histopathologic examination * No prior diagnosis of any other cancer and no history of anticancer treatment before the date of blood sample collection Exclusion Criteria (Patients) * History of other cancers before blood collection * Prior cancer treatment before blood collection * Incomplete clinical data * No consent for sample use Inclusion Criteria (Healthy Controls): * Republic of Korea nationality * No history of any cancer * Age ≥ 30 years Exclusion Criteria (Healthy Controls): * History of any malignancy * Incomplete clinical information or no consent for sample use
References
Publications (0)
Data not yet available
No reference posted for this study.