Clinical trial · Interventional
A Study of Time-Restricted Eating in Childhood Cancer Survivors
Decreasing Cardiometabolic Risk in Childhood Cancer Survivors: The STRENGTH (Survivors Engaged in Time-Restricted EatiNG After THerapy) Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will look at whether motivational sessions (including regular calls with a trained health coach) in combination with time-restricted eating (TRE) is an effective way to achieve weight loss and lower cardiometabolic risk in adult survivors of childhood cancer. The researchers will look at how effective this intervention is compared to the usual approach, which is to review educational materials and measure weight once a month. This study will not provide treatment for any disease or cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Cancer Survivors | — | UNRESOLVED | — |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Calls | Other | — | UNRESOLVED |
| Children's Oncology Group Heart Health Link | Other | — | UNRESOLVED |
| Dried blood spot | Other | — | UNRESOLVED |
| Fasting | Other | — | UNRESOLVED |
| Monthly weights | Other | — | UNRESOLVED |
| Participant Questionnaires | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention Group
- description
- Participants will be instructed to participate in time-restricted eating, building to a 16-hour fast per day (not eating or drinking calorie-enriched beverages such as soda or nutritional shakes for a 16-hour window, such as 6pm -10am or 7pm-11am). These participants will also receive motivational phone/video calls with a trained health coach, daily text message reminders of when to start and stop their fasting, and monthly weight check-ins.
- interventionNames
- Other: Monthly weights
- Other: Fasting
- Other: Calls
- Other: Participant Questionnaires
- Other: Dried blood spot
- type
- ACTIVE_COMPARATOR
- label
- Control Group
- description
- Participants will receive the standard of care electronic handouts through the Way to Health platform, and monthly weight check-ins.
- interventionNames
- Other: Children's Oncology Group Heart Health Link
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Enrolled in the Childhood Cancer Survivor Study (a cohort of 5+ year survivors of childhood cancer diagnosed at age \< 21 between 1970-1999 at 31 participating institutions in North America) * Are ≥18 years old * Self-reported body mass index ≥ 25 kg/m2 * Are not pregnant or do not intend to become pregnant in the next year * Stable weight over the past 3 months (+/- 10 pounds) * If on oral medication for insulin resistance (ie, metformin), elevated blood pressure, or dyslipidemia, medication dose must be stable (ie, unchanged \> 3 months) * Have internet access (can be via smartphone or computer). If neither device is available, the study can loan participants a Wi-Fi enabled device. Exclusion Criteria: * Do not reside in the United States * Do not speak English * Eating window \< 12 hours per 24-hour day * On insulin or GLP-1 agonist * Diagnosis of type 1 diabetes mellitus * Enrolled in a formal weight management program or other weight loss trial * History of an eating disorder
References
Publications (0)
Data not yet available