Clinical trial · Observational
Map of Tumor Genetic Actionability in Argentina
MAGenTA: Map of Tumor Genetic Actionability in Argentina
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study of the human genome laid the foundations for the search for a large number of molecular alterations related to different diseases. The Precision medicine allows us to know molecular alterations that can be detected and targeted for therapeutic purposes. There is little data in Argentina about the incidence and frequencies of alterations molecules associated with the most frequent tumors. Through the selection of a gene panel, analysis of the genetic information obtained analysis allows classifying tumors from a point of view therapeutic. On the other hand, through the same panel, markers of resistance to drugs that allow the incorporation of retreatment therapies. Together with the proposed panel, the ancestry of the patients will be evaluated to determine whether the frequencies of molecular alterations vary between the different ethnic origins of the country.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biomarkers | — | UNRESOLVED | — |
| Neoplasms Malignant | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- massively parallel sequencing
- timeFrame
- 6 months
- description
- Put into operation a massive gene sequencing platform second generation (massively parallel sequencing) for the development of a panel of precision genomic oncology in adult subjects diagnosed with solid tumors assisted at the Italian Hospital of Buenos Aires.
Secondary outcomes (2)
- measure
- Ancestry
- timeFrame
- 12 months
- description
- Perform ancestry analysis in adult subjects diagnosed with solid tumors assisted at the Italian Hospital of Buenos Aires to determine the frequency of molecular alterations associated with these tumors according to the ethnic origin of the studied population.
- measure
- Tumor genomic actionability map
- timeFrame
- 36 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Subjects 18 years of age or older Subjects diagnosed with cancer due to solid tumors who have a sample of tissue from a previous surgery or biopsy that is sufficient to be able to carry out the study methodology. Subjects who agree to sign the informed consent Exclusion Criteria: Subjects who do not agree to sign the informed consent.
References
Publications (0)
Data not yet available