Clinical trial · Observational
The Effect of Neoadjuvant Chemotherapy on Physical Functions
Investigation of the Effect of Neoadjuvant Chemotherapy on Physical Functions in Women With Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this observational study was to investigate the effect of neoadjuvant chemotherapy on physical functioning in individuals with breast cancer. The main question that the study aims to answer is how the physical functions of individuals are after neoadjuvant chemotherapy. Demographic information of the participants will be recorded and their physical status will be evaluated by determining body weight and composition, 30-second sit-and-stand test, 9-step stair ascent and descent test, one-leg stand test, upper extremity muscle strength test, lower extremity muscle strength test, tissue dielectric constant measurement, Lower Extremity Functional Scale, Global Physical Activity Questionnaire and Multidimensional Fatigue Rating Scale. In these patients who are planned to receive neoadjuvant chemotherapy for breast cancer, measurements will be made before chemotherapy (T1) and after chemotherapy (T2).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Neoadjuvant Chemotherapy | — | UNRESOLVED | — |
| Neoadjuvant Therapy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention will be performed as part of this study. However, regardless of the study, all participants will receive neoadjuvant chemotherapy. | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Breast cancer patients receiving neoadjuvant chemotherapy
- description
- Breast cancer patients who receiving neoadjuvant chemotherapy
- interventionNames
- Other: No intervention will be performed as part of this study. However, regardless of the study, all participants will receive neoadjuvant chemotherapy.
Primary outcomes (5)
- measure
- Upper limb muscle strength
- timeFrame
- It is planned to repeat the measurements 2 times: baseline and after the procedure ofneoadjuvant chemotherapy.
- description
- Since hand grip strength is correlated with upper extremity muscle strength as well as general body muscle strength and pulmonary muscle strength, upper extremity muscle strength will be evaluated by hand dynamometer.
- measure
- Lower limb muscle strength
- timeFrame
- It is planned to repeat the measurements 2 times: baseline and after the procedure ofneoadjuvant chemotherapy.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Individuals who are planned to receive neoadjuvant chemotherapy for breast cancer * Acceptance to participate in the study Exclusion Criteria: * Previous history of breast cancer * History of any other cancer * Refusal to participate in the study * Refusal to continue working
References
Publications (0)
Data not yet available